Evidence map›Paper›PMID 39339846›Full record

ArticleViruses2024

Analysis of HSV1/2 Infection Reveals an Association between HSV-2 Reactivation and Pregnancy.

Sara Dovrat, Adar Shabat, Anat Yahav-Dovrat, Zvia Soufiev, Ella Mendelson, Ela Kashi-Zagdoun, Galia Rahav

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara DovratNational Center for Herpes, Central Virology Laboratory, Ministry of Health, Sheba Medical Center, Ramat Gan 52621, Israel.
Adar ShabatNational Center for Herpes, Central Virology Laboratory, Ministry of Health, Sheba Medical Center, Ramat Gan 52621, Israel.
Anat Yahav-DovratDepartment of Radiology, Rambam Health Care Campus, Haifa 31096, Israel.ORCID 0000-0002-5154-6076
Zvia SoufievNational Center for Herpes, Central Virology Laboratory, Ministry of Health, Sheba Medical Center, Ramat Gan 52621, Israel.
Ella MendelsonNational Center for Herpes, Central Virology Laboratory, Ministry of Health, Sheba Medical Center, Ramat Gan 52621, Israel.
Ela Kashi-ZagdounNational Center for Herpes, Central Virology Laboratory, Ministry of Health, Sheba Medical Center, Ramat Gan 52621, Israel.
Galia RahavInfectious Diseases Unit, Sheba Medical Center, Ramat Gan 52621, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The herpes simplex viruses consist of the strains, HSV-1 and HSV-2, which are prevalent worldwide and lack a definitive cure. We aimed to explore the specific characteristics of HSV 1 and 2 infections, such as differences between gender assigned at birth, age at infection, site of infection, comorbidities, and effect of pregnancy, through a data analysis. Between 2011 and 2018, the Israeli Central Virology Laboratory diagnosed 9189 samples using multiplexed real-time PCR. In addition, we extracted all of the medical data for 287 females hospitalized at the Sheba Medical Center with HSV-1 (161) or HSV-2 (126) genital infections. HSV-2 was almost absent in the orofacial samples from both genders, while in other lesion sites, HSV-2 was significantly more abundant in females than in males (

Indexed as

Herpesvirus 1, HumanHerpesvirus 2, HumanPregnancy Complications, InfectiousVirus ActivationAdolescentAdultAgedFemaleHerpes GenitalisHerpes SimplexHumansIsraelMaleMiddle AgedPregnancyYoung AdultgenderHSV1HSV2pregnancyprogesteronereactivation

Identifiers

PMID39339846
PMCPMC11437484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.