Evidence map›Paper›PMID 39339756›Full record

ReviewNutrients2024

Whole Plant Extracts for Neurocognitive Disorders: A Narrative Review of Neuropsychological and Preclinical Studies.

Alessandro Piva, Giulia Benvegnù, Stefano Negri, Mauro Commisso, Sofia Ceccato, Linda Avesani, Flavia Guzzo, Cristiano Chiamulera

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mapping the Polar Neuro-Interactome ofLife (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandro PivaDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-8867-1164
Giulia BenvegnùDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Stefano NegriNBFC, National Biodiversity Future Center, 90133 Palermo, Italy.ORCID 0000-0002-4842-6831
Mauro CommissoNBFC, National Biodiversity Future Center, 90133 Palermo, Italy.ORCID 0000-0001-6474-8577
Sofia CeccatoDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Linda AvesaniNBFC, National Biodiversity Future Center, 90133 Palermo, Italy.ORCID 0000-0003-4007-7013
Flavia GuzzoNBFC, National Biodiversity Future Center, 90133 Palermo, Italy.
Cristiano ChiamuleraDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.

Funding

Project funded under the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.4 - Call for tender No. 3138 of 16 December 2021, rectified by Decree n.3175 of 18 December 2021 of Italian Ministry of University and Research funde Project code CN_00000033, Concession Decree No. 1034 of 17 June 2022 adopted by the Italian Ministry of University and Research, CUP B33C22000660001, Project title "National Biodiversi-ty Future Center - NBFC
6 · The paper itself

Abstract

The incidence of neurodegenerative disorders like Alzheimer's or Parkinson's Disease, characterized by a progressive cognitive decline, is rising worldwide. Despite the considerable efforts to unveil the neuropsychological bases of these diseases, there is still an unmet medical need for effective therapies against cognitive deficits. In recent years, increasing laboratory evidence indicates the potential of phytotherapy as an integrative aid to improve cognitive functions. In this review, we describe the data of plant whole extracts or single compounds' efficacy on validated preclinical models and neuropsychological tests, aiming to correlate brain mechanisms underlying rodent behavioral responses to human findings. After a search of the literature, the overview was limited to the following plants:

Indexed as

PhytotherapyPlant ExtractsAnimalsCognitionCognitive DysfunctionDisease Models, AnimalGinkgo bilobaHumansNeurocognitive DisordersNeuropsychological TestsPlant Extractsbioactive phytochemicalscognitive functionshumansneuropsychological testsplant extractsrodents

Identifiers

PMID39339756
PMCPMC11434991

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.