Evidence map›Paper›PMID 39339754›Full record

ReviewNutrients2024

Supplementation with Folic Acid or 5-Methyltetrahydrofolate and Prevention of Neural Tube Defects: An Evidence-Based Narrative Review.

María de Lourdes Samaniego-Vaesken, Carmen Morais-Moreno, Alejandra Carretero-Krug, Ana María Puga, Ana María Montero-Bravo, Teresa Partearroyo, Varela-Moreiras Gregorio

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Integrative Analysis of Key Signalling Pathways in Neural Tube Defects: From Molecular Mechanisms to Therapeutic Strategies.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2025
    Review
  13. Development of a Prognostic Model for MACE in Atherosclerosis Based on MTHFR and Serum Markers.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María de Lourdes Samaniego-VaeskenGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0001-7323-4420
Carmen Morais-MorenoGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0002-1289-3745
Alejandra Carretero-KrugGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0002-6559-8002
Ana María PugaGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0003-2836-4642
Ana María Montero-BravoGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0001-5103-3732
Teresa PartearroyoGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0002-4401-1233
Varela-Moreiras GregorioGrupo USP-CEU de Excelencia "Nutrición para la vida (Nutrition for Life)", Ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0001-5158-4999

Funding

ITF RESEARCH PHARMA, S.L.U OTRI2023-23
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dietary SupplementsFolic AcidNeural Tube DefectsTetrahydrofolatesAnimalsEvidence-Based MedicineFemaleHumansPregnancy5-methyltetrahydrofolateFolic AcidTetrahydrofolates5-methyltetrahydrofolatefolatesfolic acidfortificationhomocysteineneural tube defectsNTDpregnancysupplementation

Identifiers

PMID39339754
PMCPMC11435031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.