Evidence map›Paper›PMID 39339746›Full record

ArticleNutrients2024

Botanical Bioflavonoid Composition from

Mesfin Yimam, Teresa Horm, Alexandria O'Neal, Paola Chua, Ping Jiao, Mei Hong, Qi Jia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mesfin YimamUnigen Inc., 2121 South State Street, Suite #400, Tacoma, WA 98405, USA.ORCID 0000-0001-5009-1586
Teresa HormDepartment of Biology, Pacific Lutheran University, 12180 Park Ave. S, Tacoma, WA 98447, USA.
Alexandria O'NealSeagen Pfizer, 21717 30th Dr SE, Bothell, WA 98021, USA.
Paola ChuaWashington State Department of Health, 1610 NE 150th St, Shoreline, WA 98155, USA.
Ping JiaoUnigen Inc., 2121 South State Street, Suite #400, Tacoma, WA 98405, USA.
Mei HongUnigen Inc., 2121 South State Street, Suite #400, Tacoma, WA 98405, USA.
Qi JiaUnigen Inc., 2121 South State Street, Suite #400, Tacoma, WA 98405, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and chronic inflammation create a perpetual cycle in the elderly, where impaired immune function amplifies susceptibility to oxidative damage, and oxidative stress further weakens the immune response. This cycle is particularly detrimental to the respiratory system of the elderly, which is an easy target for constant exogenous harmful attacks during cold/flu season or under heavy air pollution. Herbal medicines that protect respiratory function are seen as safer alternatives to conventional therapies; however, there is limited availability of scientifically validated, safe, and effective natural supplements for these conditions. In this study, we evaluated a standardized bioflavonoid composition, UP446, that contains bioactives from the roots of

Indexed as

AcaciaAntioxidantsCyclophosphamideGalactoseImmunosenescencePlant ExtractsScutellaria baicalensisAnimalsFlavonoidsMaleMiceOxidative StressAntioxidantsCyclophosphamideFlavonoidsGalactosePlant ExtractsScutellaria baicalensis extractAcacia catechuantibody IgAimmunosenescenceNK cellspolyphenolsrespiratory protectionScutellaria baicalensisT cells

Identifiers

PMID39339746
PMCPMC11434731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.