Evidence map›Paper›PMID 39339694›Full record

ArticleNutrients2024

A Dose-Response Study on the Relationship between White Meat Intake and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Southern Italy: Results from the Nutrihep Study.

Davide Guido, Nicole Cerabino, Martina Di Chito, Rossella Donghia, Cristiana Randazzo, Caterina Bonfiglio, Gianluigi Giannelli, Giovanni De Pergola

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Davide GuidoUnit of Data Science, National Institute of Gastroenterology "Saverio de Bellis", IRCCS Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-3291-3686
Nicole CerabinoCenter of Nutrition for the Research and the Care of Obesity and Metabolic Diseases, National Institute of Gastroenterology IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.
Martina Di ChitoCenter of Nutrition for the Research and the Care of Obesity and Metabolic Diseases, National Institute of Gastroenterology IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.
Rossella DonghiaUnit of Data Science, National Institute of Gastroenterology "Saverio de Bellis", IRCCS Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-9140-673X
Cristiana RandazzoDipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza (PROMISE), University of Palermo, I-90127 Palermo, Italy.ORCID 0000-0001-9081-6190
Caterina BonfiglioUnit of Data Science, National Institute of Gastroenterology "Saverio de Bellis", IRCCS Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-8650-348X
Gianluigi GiannelliScientific Direction, National Institute of Gastroenterology "Saverio de Bellis", IRCCS Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-5140-8060
Giovanni De PergolaCenter of Nutrition for the Research and the Care of Obesity and Metabolic Diseases, National Institute of Gastroenterology IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0003-0020-3273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Metabolic dysfunction-associated liver disease (MASLD) is one of the most important causes of liver disease worldwide. Meat consumption is a growing trend and white meat has been shown to have beneficial effects on cardiometabolic risk factors. The aim of this study was to investigate the dose-response relationship between white meat intake and MASLD at survey level in a Southern Italy setting. (2) Methods: This cross-sectional study encompassed 1192 subjects (509 males, 42.7%) without missing data from the second wave of the NUTRIHEP cohort (2014-2016). Adjusted dose-response modeling was employed for statistical analysis; (3) Results: There were 587 subjects with MASLD (49.2%), i.e., 278 males (54.6%) and 309 females (45.2%). By increasing the intake, an unfavorable influence of white meat on MASLD was significantly revealed in females, whereas a protective effect of white meat was detectable in males. Male sex was shown to be involved in other associations in this study, such as influencing the preference for specific foods such as poultry and chicken skin. (4) Conclusions: Our data suggest that white meat does not have a clear-cut independent dose-response effect on MASLD, but sex may be a trigger moderator for age and BMI, with an increasing unfavorable effect of white meat in women, and a favorable effect in men.

Indexed as

DietAdultAgedAnimalsCardiometabolic Risk FactorsCross-Sectional StudiesFemaleHumansItalyMaleMeatMiddle AgedNon-alcoholic Fatty Liver DiseaseRisk FactorsSex FactorsDAGdose–response modelinglogistic regressionMASLDsurveywhite meat intake

Identifiers

PMID39339694
PMCPMC11435003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.