Evidence map›Paper›PMID 39339353›Full record

ArticleMolecules (Basel, Switzerland)2024

Electronic Nose Analysis of Exhaled Breath Volatile Organic Compound Profiles during Normoxia, Hypoxia, and Hyperoxia.

Pasquale Tondo, Giulia Scioscia, Marcin Di Marco, Vitaliano Nicola Quaranta, Terence Campanino, Giuseppe Palmieri, Andrea Portacci, Andrea Santamato, Donato Lacedonia, Giovanna Elisiana Carpagnano and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pasquale TondoRespiratory Diseases, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-1202-8567
Giulia SciosciaRespiratory Diseases, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-2667-077X
Marcin Di MarcoRespiratory Diseases, Department DiBrain, University of Bari, 70124 Bari, Italy.
Vitaliano Nicola QuarantaRespiratory Diseases, Department DiBrain, University of Bari, 70124 Bari, Italy.ORCID 0000-0001-9920-780X
Terence CampaninoRespiratory Diseases, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Giuseppe PalmieriRespiratory Diseases, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Andrea PortacciRespiratory Diseases, Department DiBrain, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-6127-2486
Andrea SantamatoUnit Physical Medicine and Rehabilitation Section, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-1452-8485
Donato LacedoniaRespiratory Diseases, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Giovanna Elisiana CarpagnanoRespiratory Diseases, Department DiBrain, University of Bari, 70124 Bari, Italy.
Silvano DragonieriRespiratory Diseases, Department DiBrain, University of Bari, 70124 Bari, Italy.ORCID 0000-0003-1563-6864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates volatile organic compound (VOC) profiles in the exhaled breath of normal subjects under different oxygenation conditions-normoxia (FiO2 21%), hypoxia (FiO2 11%), and hyperoxia (FiO2 35%)-using an electronic nose (e-nose). We aim to identify significant differences in VOC profiles among the three conditions utilizing principal component analysis (PCA) and canonical discriminant analysis (CDA). Our results indicate distinct VOC patterns corresponding to each oxygenation state, demonstrating the potential of e-nose technology in detecting physiological changes in breath composition (cross-validated accuracy values: FiO2 21% vs. FiO2 11% = 63%, FiO2 11% vs. FiO2 35% = 65%, FiO2 21% vs. FiO2 35% = 71%, and

Indexed as

Breath TestsElectronic NoseExhalationHyperoxiaHypoxiaPrincipal Component AnalysisVolatile Organic CompoundsAdultDiscriminant AnalysisFemaleHumansMaleVolatile Organic Compoundselectronic noseexhaled breathhyperoxiahypoxiavolatile organic compounds

Identifiers

PMID39339353
PMCPMC11434471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.