Evidence map›Paper›PMID 39339310›Full record

ArticleMolecules (Basel, Switzerland)2024

An Unprecedented 4,8-Cycloeudesmane, Further New Sesquiterpenoids, a Triterpene, Steroids, and a Lignan from the Resin of

Anna Unterholzner, Katrin Kuck, Anna Weinzierl, Bartosz Lipowicz, Jörg Heilmann

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna UnterholznerInstitute of Pharmaceutical Biology, University of Regensburg, Universitätsstr. 31, D-93053 Regensburg, Germany.ORCID 0000-0003-2596-0537
Katrin KuckInstitute of Pharmaceutical Biology, University of Regensburg, Universitätsstr. 31, D-93053 Regensburg, Germany.ORCID 0009-0005-0224-1646
Anna WeinzierlInstitute of Pharmaceutical Biology, University of Regensburg, Universitätsstr. 31, D-93053 Regensburg, Germany.
Bartosz LipowiczRepha GmbH Biologische Arzneimittel, Alt-Godshorn 87, D-30855 Langenhagen, Germany.
Jörg HeilmannInstitute of Pharmaceutical Biology, University of Regensburg, Universitätsstr. 31, D-93053 Regensburg, Germany.

Funding

Repha (Germany) Repha-7209
6 · The paper itself

Abstract

Myrrh has a long tradition in the treatment of inflammatory diseases. However, many of its (active) constituents are still unknown. In the present study, secondary metabolites were isolated from an ethanolic extract by various separation methods (liquid-liquid partition, silica and RP18 flash chromatography, CPC, and preparative HPLC), their structures were elucidated with NMR spectroscopy and mass spectrometry, and the selected compounds were tested for their effect on LPS-induced NO production by RAW 264.7 murine macrophages. Among the isolated substances are 17 sesquiterpenes (

Indexed as

Anti-Inflammatory AgentsCommiphoraLignansSesquiterpenesSteroidsTriterpenesAnimalsLipopolysaccharidesMacrophagesMagnetic Resonance SpectroscopyMiceMolecular StructureNitric OxidePlant ExtractsRAW 264.7 CellsResins, PlantAnti-Inflammatory AgentsLignansLipopolysaccharidesNitric OxidePlant ExtractsResins, PlantSesquiterpenesSteroidsTriterpenesanti-inflammatoryBurseraceaeCommiphora myrrhacycloeudesmanelignanphytosterolsesquiterpene lactone

Identifiers

PMID39339310
PMCPMC11434423

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.