Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Zohra BouchekhouChemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Blida 1, Road of Soumaa, BP 270, Blida 09000, Algeria.ORCID 0000-0002-9896-8284
Amel Hadj Ziane-ZafourChemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Blida 1, Road of Soumaa, BP 270, Blida 09000, Algeria.
Florentina Geanina LupascuDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy of Iași, 16 Universitaty Street, 700115 Iași, Romania.
Bianca-Ștefania ProfireDepartment of Internal Medicine, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy of Iasi, 16 University Street, 700115 Iași, Romania.ORCID 0000-0003-1792-7139
Alina Nicolescu"Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, 700487 Iasi, Romania.ORCID 0000-0001-7022-8893
Denisse-Iulia Bostiog"Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, 700487 Iasi, Romania.
Florica Doroftei"Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, 700487 Iasi, Romania.
Ioan-Andrei Dascalu"Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-0715-6855
Cristian-Dragoș Varganici"Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-4813-9162
Mariana Pinteala"Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-4021-982X
Lenuta ProfireDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy of Iași, 16 Universitaty Street, 700115 Iași, Romania.ORCID 0000-0002-7953-3023
Tudor PintealaDepartment of Orthopedics and Traumatology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy of Iasi, 16 University Street, 700115 Iași, Romania.ORCID 0000-0001-7664-0918
Bachir BouzidChemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Blida 1, Road of Soumaa, BP 270, Blida 09000, Algeria.
Although niflumic acid (NA) is one of the most used non-steroidal anti-inflammatory drugs, it suffers from poor solubility, low bioavailability, and significant adverse effects. To address these limitations, the complexation of NA with cyclodextrins (CDs) is a promising strategy. However, complexing CDs with low molecular weight drugs like NA can lead to low CE. This study explores the development of inclusion complexes of NA with 2-hydroxypropyl-β-cyclodextrin (2HP-β-CD), including the effect of converting NA to its sodium salt (NAs) and adding hydroxypropyl methylcellulose (HPMC) on complex formation. Inclusion complexes were prepared using co-evaporation solvent and freeze-drying methods, and their CE and Ks were determined through a phase solubility study. The complexes were characterized using physicochemical analyses, including FT-IR, DSC, SEM, XRD, DLS, UV-Vis,
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Binary and Ternary Inclusion Complexes of Niflumic Acid: Synthesis, Characterization, and Dissolution Profile. · full record | OpenQuestion