Evidence map›Paper›PMID 39339154›Full record

ArticlePharmaceutics2024

Self-Microemulsifying Drug Delivery System to Enhance Oral Bioavailability of Berberine Hydrochloride in Rats.

Xiaolan Chen, Haifeng Yang, Longyu Shi, Yujuan Mao, Lin Niu, Jing Wang, Haifeng Chen, Jiping Jia, Jingxuan Wang, Jiajie Xue and 4 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Berberine: A Negentropic Modulator for Multi-System Coordination.International journal of molecular sciences · 2026
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiaolan ChenDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Haifeng YangDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Longyu ShiCollege of Life Sciences, China Pharmaceutical University, Nanjing 210009, China.ORCID 0009-0008-6089-9317
Yujuan MaoDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Lin NiuDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Jing WangDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Haifeng ChenDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Jiping JiaDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Jingxuan WangDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Jiajie XueDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.
Yan ShenDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China.
Chunli ZhengDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China.
Yu TianSchool of Medicine, Shanghai University, Shanghai 200444, China.
Yi ZhengDepartment of Pharmaceutics, Jiangsu Agri-Animal Husbandry Vocational College, No. 8, Fenghuang East Road, Taizhou 225300, China.

Funding

Jiangsu Agri-animal Husbandry Vocational College Project NSF2022ZR05Major project of Basic Science (Natural science) research in colleges and universities of Jiangsu Province 23KJA360001Qinglan Engineering in Jiangsu Province, Tibet Autonomous Region Science and Technology Department Project XZ202101YD0001CStudents Innovation and Entrepreneurship Training Program of Vocational College in Jiangsu Province G-2023-0726Taizhou Science and Technology Supporting Agriculture Project TN202218
6 · The paper itself

Abstract

Berberine hydrochloride (BH) is a versatile bioactive compound derived from the plants of the

Indexed as

berberine hydrochloridebioavailabilityin vitro dissolutionSMEDDS

Identifiers

PMID39339154
PMCPMC11435259

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.