Evidence map›Paper›PMID 39339025›Full record

ArticlePolymers2024

Preparation and Stability Study of an Injectable Hydrogel for Artificial Intraocular Lenses.

Haifeng Cui, Pengfei Li, Zekun Su, Shiqiang Guan, He Dong, Xufeng Dong

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Nanotechnology-Based Treatment for Ophthalmic Diseases.International journal of nanomedicine · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haifeng CuiSchool of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.
Pengfei LiSchool of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.
Zekun SuSchool of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.
Shiqiang GuanSchool of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.
He DongDepartment Ophthalmology, The Third People's Hospital of Dalian, Dalian 116033, China.
Xufeng DongSchool of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0001-5556-280X

Funding

Fundamental Research Funds for the Central Universities of China DUT23BK023
6 · The paper itself

Abstract

Currently available intraocular lenses (IOLs) on the market often differ significantly in elastic modulus compared to the natural human lens, which impairs their ability to respond effectively to the tension of the ciliary muscles for focal adjustment after implantation. In this study, we synthesized a polyacrylamide-sodium acrylate hydrogel (PAH) through the cross-linking polymerization of acrylamide and sodium acrylate. This hydrogel possesses excellent biocompatibility and exhibits several favorable properties. Notably, the hydrogel demonstrates high transparency (94%) and a refractive index (1.41 ± 0.07) that closely matches that of the human lens (1.42). Additionally, it shows strong compressive strength (14.00 kPa), good extensibility (1400%), and an appropriate swelling ratio (50 ± 2.5%). Crucially, the tensile modulus of the hydrogel is 2.07 kPa, which closely aligns with the elastic modulus of the human lens (1.70-2.10 kPa), enabling continuous focal adjustment under the tension exerted by the ciliary muscles.

Indexed as

artificial intraocular lenscataract treatmenthydrogeltensile modulusvariable focus

Identifiers

PMID39339025
PMCPMC11434676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.