Evidence map›Paper›PMID 39339011›Full record

ReviewPathogens (Basel, Switzerland)2024

Oral Microbiota and the Risk of Gastrointestinal Cancers-A Narrative Literature Review.

Kinga Knop-Chodyła, Anna Kochanowska-Mazurek, Zuzanna Piasecka, Aneta Głaz, Ewelina Weronika Wesołek-Bielaska, Kinga Syty, Alicja Forma, Jacek Baj

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. From gut to mouth: salivary signatures of carcinogenic microbiota.Frontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. New advances in oral microbiology and tumor research.World journal of clinical oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kinga Knop-ChodyłaUniversity Clinical Hospital Number 4 in Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.ORCID 0000-0002-7866-4830
Anna Kochanowska-MazurekStefan Cardinal Wyszynski Province Specialist Hospital, al. Kraśnicka 100, 20-718 Lublin, Poland.ORCID 0000-0003-3595-9206
Zuzanna PiaseckaSaint Queen Jadwiga's Regional Clinical Hospital Number 2 in Rzeszow, Lwowska 60, 35-301 Rzeszów, Poland.ORCID 0000-0001-7896-0907
Aneta GłazFaculty of Medicine, Medical University of Lublin, al. Racławickie 1, 20-059 Lublin, Poland.ORCID 0000-0002-8220-0510
Ewelina Weronika Wesołek-BielaskaUniversity Clinical Hospital Number 4 in Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.ORCID 0000-0001-7819-2661
Kinga SytyInstitute of Health Sciences, John Paul the II Catholic University of Lublin, Konstantynów 1G, 20-708 Lublin, Poland.
Alicja FormaDepartment of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0000-0001-8714-7627
Jacek BajDepartment of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0002-1372-8987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human body is colonized by trillions of microorganisms in a symbiotic relationship. The oral cavity represents one of the most abundant microbial habitats in our body. Advances in sequencing techniques provide a more detailed understanding of the oral microbiota and how imbalances between bacteria, the phenomenon of dysbiosis, can affect not only the development of dental caries or inflammation within the oral cavity but also systemic diseases and cancers in distant locations. This narrative review evaluates the relationship between oral microbiota and its impact on gastrointestinal cancers. Using the keywords "oral microbiota 'AND' gastrointestinal cancers", the PubMed Web of Science and Scopus databases were searched for articles published between 2014 and 2024. Based on the review, the relationship between oral microbiota and oral, esophageal, gastric, colorectal, hepatocellular, and pancreatic cancers was described. Potential oncogenic mechanisms exploited by the microbiota such as the production of pro-inflammatory cytokines, induction of abnormal immune responses, and disruption of cell metabolic pathways were assessed. Further research and a thorough understanding of the impact of the oral microbiota on the development of cancers of the gastrointestinal tract may play a key role in their prevention, diagnosis, and treatment in the future.

Indexed as

DysbiosisGastrointestinal NeoplasmsMicrobiotaMouthHumanscolorectal canceresophageal cancergastric cancergastrointestinal cancerhepatocellular carcinomaoral canceroral microbiotapancreatic cancer

Identifiers

PMID39339011
PMCPMC11434710

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.