Evidence map›Paper›PMID 39338594›Full record

ReviewMicroorganisms2024

An Overview of the Recent Advances in Antimicrobial Resistance.

Manuela Oliveira, Wilson Antunes, Salete Mota, Áurea Madureira-Carvalho, Ricardo Jorge Dinis-Oliveira, Diana Dias da Silva

Abstract readReview
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  13. A Codesigned Approach to Develop Tailored Antimicrobial Stewardship Strategies in Bangladesh: A Social-Ecological Systems Framework Analysis.Health expectations : an international journal of public participation in health care and health policy · 2026
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manuela OliveiraAssociate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, Avenida Central de Gandra 1317, 4585-116 Gandra, Portugal.ORCID 0000-0001-5785-7521
Wilson AntunesInstituto Universitário Militar, CINAMIL, Unidade Militar Laboratorial de Defesa Biológica e Química, Avenida Doutor Alfredo Bensaúde, 4 piso, do LNM, 1849-012 Lisbon, Portugal.
Salete MotaULSEDV-Unidade Local De Saúde De Entre Douro Vouga, Unidade de Santa Maria da Feira e Hospital S. Sebastião, Rua Dr. Cândido Pinho, 4520-211 Santa Maria da Feira, Portugal.
Áurea Madureira-CarvalhoAssociate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, Avenida Central de Gandra 1317, 4585-116 Gandra, Portugal.ORCID 0000-0002-7569-6802
Ricardo Jorge Dinis-OliveiraAssociate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, Avenida Central de Gandra 1317, 4585-116 Gandra, Portugal.ORCID 0000-0001-7430-6297
Diana Dias da SilvaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, Avenida Central de Gandra 1317, 4585-116 Gandra, Portugal.ORCID 0000-0002-7331-9157

Funding

Fundação para a Ciência e Tecnologia UIDP/04378/2020, UIDB/04378/2020, LA/P/0140/2020, UIDB/50006
6 · The paper itself

Abstract

Antimicrobial resistance (AMR), frequently considered a major global public health threat, requires a comprehensive understanding of its emergence, mechanisms, advances, and implications. AMR's epidemiological landscape is characterized by its widespread prevalence and constantly evolving patterns, with multidrug-resistant organisms (MDROs) creating new challenges every day. The most common mechanisms underlying AMR (i.e., genetic mutations, horizontal gene transfer, and selective pressure) contribute to the emergence and dissemination of new resistant strains. Therefore, mitigation strategies (e.g., antibiotic stewardship programs-ASPs-and infection prevention and control strategies-IPCs) emphasize the importance of responsible antimicrobial use and surveillance. A One Health approach (i.e., the interconnectedness of human, animal, and environmental health) highlights the necessity for interdisciplinary collaboration and holistic strategies in combating AMR. Advancements in novel therapeutics (e.g., alternative antimicrobial agents and vaccines) offer promising avenues in addressing AMR challenges. Policy interventions at the international and national levels also promote ASPs aiming to regulate antimicrobial use. Despite all of the observed progress, AMR remains a pressing concern, demanding sustained efforts to address emerging threats and promote antimicrobial sustainability. Future research must prioritize innovative approaches and address the complex socioecological dynamics underlying AMR. This manuscript is a comprehensive resource for researchers, policymakers, and healthcare professionals seeking to navigate the complex AMR landscape and develop effective strategies for its mitigation.

Indexed as

antibiotic stewardship programsantimicrobial resistanceepidemiologymechanismsnovel therapeuticsOne Health approachpolicy interventions

Identifiers

PMID39338594
PMCPMC11434382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.