Evidence map›Paper›PMID 39338545›Full record

ArticleMicroorganisms2024

In Vitro Antimicrobial Synergistic Activity and the Mechanism of the Combination of Naringenin and Amikacin Against Antibiotic-Resistant

Lankun Yi, Mingze Cao, Xu Chen, Yubin Bai, Weiwei Wang, Xiaojuan Wei, Yuxiang Shi, Yongying Zhang, Tenghe Ma, Zhen Zhu and 1 more

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. n-Butanol Extract ofCurrent issues in molecular biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Adjuvant potential ofPharmaceutical biology · 2025
    Article
  9. Anti-infective synergy of3 Biotech · 2025
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lankun YiCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Mingze CaoCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Xu ChenCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Yubin BaiLanzhou Institute of Husbandry and Pharmaceutical Sciences, Lanzhou 730050, China.
Weiwei WangLanzhou Institute of Husbandry and Pharmaceutical Sciences, Lanzhou 730050, China.
Xiaojuan WeiLanzhou Institute of Husbandry and Pharmaceutical Sciences, Lanzhou 730050, China.
Yuxiang ShiCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Yongying ZhangCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Tenghe MaCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Zhen ZhuCollege of Life Science and Food Engineering, Hebei University of Engineering, Hanshan District, Handan 056038, China.
Jiyu ZhangLanzhou Institute of Husbandry and Pharmaceutical Sciences, Lanzhou 730050, China.

Funding

Earmarked fund for Hebei Agriculture Research System HBCT2024270202;HBCT2024260205Key Research and Development Projects of Hebei 22326617DNatural Science Foundation of Hebei Province C2023402003;C2024402032the Chinese Academy of Agricultural Sciences Innovation Project 25-LZIHPS-05the National Beef Cattle and Yak Industry Technology Systemthe CARS-37the National Natural Science Foundation of China 32202860
6 · The paper itself

Abstract

Bacterial drug resistance is becoming an increasingly serious problem, and the development of antibacterial synergists is urgently needed. Combining existing antibiotics with promising nonantibiotic agents is one strategy that has been shown to be effective at overcoming the widespread emergence of antibiotic-resistant pathogens. In this study, we investigated the antibacterial activities and mechanism of naringenin (NG) combined with amikacin (AMK) against multidrug-resistant

Indexed as

amikacinantibacterial mechanismEscherichia colinaringeninsynergistic effect

Identifiers

PMID39338545
PMCPMC11433787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.