Evidence map›Paper›PMID 39338386›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

In Vitro Study of Cyano-Phycocyanin Release from Hydrogels and Ex Vivo Study of Skin Penetration.

Daiva Galinytė, Jurga Bernatoniene, Modestas Žilius, Kristina Rysevaitė-Kyguolienė, Arūnas Savickas, Jūratė Karosienė, Vitalis Briedis, Dainius Haroldas Pauža, Nijolė Savickienė

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Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daiva GalinytėDepartment of Pharmacognosy, Faculty of Pharmacy, Academy of Medicine, Lithuanian University of Health Sciences, Sukilėlių av. 13, 50162 Kaunas, Lithuania.
Jurga BernatonieneDepartment of Drug Technology and Social Pharmacy, Faculty of Pharmacy, Academy of Medicine, Lithuanian University of Health Sciences, Sukilėlių av. 13, 50162 Kaunas, Lithuania.ORCID 0000-0003-1744-2932
Modestas ŽiliusDepartment of Clinical Pharmacy, Faculty of Pharmacy, Academy of Medicine, Lithuanian University of Health Sciences, Sukilėlių av. 13, 50162 Kaunas, Lithuania.ORCID 0000-0002-3358-6162
Kristina Rysevaitė-KyguolienėInstitute of Anatomy, Faculty of Medicine, Academy of Medicine, Lithuanian University of Health Sciences, Mickevičiaus St. 9, 44307 Kaunas, Lithuania.ORCID 0009-0000-5566-1170
Arūnas SavickasDepartment of Drug Technology and Social Pharmacy, Faculty of Pharmacy, Academy of Medicine, Lithuanian University of Health Sciences, Sukilėlių av. 13, 50162 Kaunas, Lithuania.
Jūratė KarosienėLaboratory of Algology and Microbial Ecology, Nature Research Centre, Akademijos St. 2, 08412 Vilnius, Lithuania.
Vitalis BriedisDepartment of Clinical Pharmacy, Faculty of Pharmacy, Academy of Medicine, Lithuanian University of Health Sciences, Sukilėlių av. 13, 50162 Kaunas, Lithuania.
Dainius Haroldas PaužaInstitute of Anatomy, Faculty of Medicine, Academy of Medicine, Lithuanian University of Health Sciences, Mickevičiaus St. 9, 44307 Kaunas, Lithuania.
Nijolė SavickienėDepartment of Pharmacognosy, Faculty of Pharmacy, Academy of Medicine, Lithuanian University of Health Sciences, Sukilėlių av. 13, 50162 Kaunas, Lithuania.ORCID 0000-0001-9627-8231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study explored the most suitable materials for incorporating cyano-phycocyanin (C-PC) into hydrogels, focusing on maintaining the C-PC's long-term structural integrity and stabilityNext, the release of C-PC from the hydrogels and its skin penetration were investigated.

methodsA series of 1% (

resultsThe findings demonstrated that sodium alginate (Sigma-Aldrich, St. Louis, MO, USA), hydroxyethyl cellulose (HEC) (Sigma-Aldrich, St. Louis, MO, USA), and Soligel

conclusionPG's ability to enhance the release of C-PC from the hydrogel, coupled with its capacity to modify the skin barrier ex vivo, facilitates the penetration of C-PC into the stratum corneum.

Indexed as

cyano-phycocyaninex vivo skin penetrationhydrogelin vitro drug releasepropylene glycolsodium alginate

Identifiers

PMID39338386
PMCPMC11434783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.