Evidence map›Paper›PMID 39338327›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Use of Ketamine in Patients with Multifactorial Neuropathic Pain: A Systematic Review and Meta-Analysis.

Alejandro Bruna-Mejias, Vicente Baeza, Javiera Gamboa, Belen Baez Flores, Jessica San Martin, Constanza Astorga, Javiera Leyton, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandra Suazo-Santibañez and 3 more

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alejandro Bruna-MejiasDepartamento de Ciencias y Geografía, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Valparaíso 2360072, Chile.
Vicente BaezaDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.
Javiera GamboaDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.
Belen Baez FloresDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.
Jessica San MartinDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.ORCID 0009-0007-7689-8573
Constanza AstorgaFaculty of Medicine and Science, Universidad San Sebastián, Santiago 8420524, Chile.
Javiera LeytonDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.
Pablo Nova-BaezaDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.ORCID 0000-0003-0098-0224
Mathias Orellana-DonosoFaculty of Medicine and Science, Universidad San Sebastián, Santiago 8420524, Chile.
Alejandra Suazo-SantibañezFaculty of Health and Social Sciences, Universidad de las Américas, Santiago 8370040, Chile.
Alvaro Becerra-FarfánEscuela de Fonoaudiología & Departamento de Ciencias Química y Biológicas, Facultad de Ciencias de la Salud, Universidad Bernardo O'Higgins, Santiago 8320000, Chile.ORCID 0000-0001-8182-6135
Gustavo Oyanedel-AmaroFacultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago 8910060, Chile.
Juan Jose Valenzuela-FuenzalidaDepartamento de Morfología, Facultad de Medicina, Universidad Andres Bello, Santiago 8420524, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropathic pain (NP) is a heterogeneous group of conditions characterized by the experience of a number of sensory disturbances including pain, burning sensations, paroxysms of stabbing pain, dysesthesias, allodynia, and hyperalgesia. The above-mentioned sensations may occur in a specific dermatome area or other delimited region of the body. The objective of this review was to analyze the evidence for ketamine in multifactorial neuropathic pain. The research group systematically searched the databases MEDLINE (via PubMed), EMBASE, SCOPUS, the Cochrane Central Register of Controlled Trials, the Cumulative Index to Nursing and Allied Health Literature (Cinahl), and the Web of Science. The findings of this review show that different forms of low doses of ketamine (LDK) do not present statistically significant changes for any of the scales included. In this study, the total symptom score [standardized mean difference (SMD) = -3.59, confidence interval (CI) = -4.16 to -3.02, and

Indexed as

ketamineneuropathic painpharmacologypolyneuropathy

Identifiers

PMID39338327
PMCPMC11435086

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.