Evidence map›Paper›PMID 39338267›Full record

ReviewJournal of personalized medicine2024

Oral Care in Head and Neck Radiotherapy: Proposal for an Oral Hygiene Protocol.

Giacomo Spinato, Valentina Schiavon, Sara Torvilli, Stefano Carraro, Federica Amato, Antonio Daloiso, Adolfo Di Fiore, Vittorio Favero, Leonardo Franz, Gino Marioni and 4 more

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Quality assurance and improvement in dental oncology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Educational Interventions in Oral Hygiene for Patients Undergoing Head and Neck Cancer Radiotherapy: A Feasibility Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giacomo SpinatoDepartment of Neuroscience, Section of Otolaryngology, University of Padova, 35121 Padova, Italy.ORCID 0000-0001-5295-5077
Valentina SchiavonDepartment of Neuroscience, School of Dentistry, University of Padova, 35121 Padova, Italy.
Sara TorvilliDepartment of Neuroscience, School of Dentistry, University of Padova, 35121 Padova, Italy.
Stefano CarraroDepartment of Neuroscience, Section of Otolaryngology, University of Padova, 35121 Padova, Italy.
Federica AmatoDepartment of Neuroscience, Section of Otolaryngology, University of Padova, 35121 Padova, Italy.
Antonio DaloisoDepartment of Neuroscience, Section of Otolaryngology, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-3687-8814
Adolfo Di FioreDepartment of Neuroscience, School of Dentistry, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-1766-2567
Vittorio FaveroDepartment of Neuroscience, Section of Maxillofacial Surgery, University of Padova, 35121 Padova, Italy.
Leonardo FranzDepartment of Neuroscience, Section of Audiology and Phoniatry, University of Padova, Treviso Hospital, 31100 Treviso, Italy.
Gino MarioniDepartment of Neuroscience, Section of Audiology and Phoniatry, University of Padova, Treviso Hospital, 31100 Treviso, Italy.ORCID 0000-0001-8751-0588
Cosimo de FilippisDepartment of Neuroscience, Section of Audiology and Phoniatry, University of Padova, Treviso Hospital, 31100 Treviso, Italy.
Cristoforo FabbrisDepartment of Medicine DIMED, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-4476-9802
Enzo EmanuelliAULSS 2 Marca Trevigiana, Section of Otolaryngology, Treviso Hospital, 31100 Treviso, Italy.
Piero NicolaiDepartment of Neuroscience, Section of Otolaryngology, University of Padova, 35121 Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aims to provide a comprehensive overview of the literature on the oral side effects caused by radiotherapy for head and neck cancers. Various treatments are examined to mitigate these sequelae, and a protocol is proposed for dentists and dental hygienists to manage oncological patients. A literature search was conducted to select relevant articles addressing the effects of radiotherapy treatments on the oral cavity, with a particular focus on the development of mucositis, candidiasis, changes in salivary pH, trismus, fibrosis, and alterations in the oral biofilm. PubMed and MedLine were used as search engines, with keyword combinations including: head and neck cancer, mucositis, candida, dental care, dental hygiene, epidemiology, oral microbiome, biofilm, trismus, fibrosis, and salivary pH. A total of 226 articles were identified, spanning the period from 1998 to 2023. Articles deemed inappropriate or in languages other than English or Italian were excluded. A management protocol for oncological patients was proposed, divided into two phases: home-based and professional. Despite the advancements in intensity-modulated radiation therapy, it is impossible to completely avoid damage to healthy tissues. Preventive education and counseling in the dental chair, ongoing motivation, and education about oral hygiene are crucial to combine a good therapeutic outcome with an improved quality of life for the patient.

Indexed as

head and neck cancerhygieneoral cavityradiotherapy

Identifiers

PMID39338267
PMCPMC11433007

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.