Evidence map›Paper›PMID 39338245›Full record

ArticleJournal of personalized medicine2024

The Impact of Frailty and Gender Differences on Hospitalization and Complications in Proximal Femoral Pathological Fractures: A Cross-Sectional Study.

Alessandro El Motassime, Elisa Pesare, Andrea Russo, Sara Salini, Giordana Gava, Carla Recupero, Tommaso Giani, Marcello Covino, Giulio Maccauro, Raffaele Vitiello

Registry-linked trialAbstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07358455 (Identification of Pre-prosthetic Revision Markers Predictive of Outcome in Patients With Periprosthetic Infection), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07358455 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Identification of Pre-prosthetic Revision Markers Predictive of Outcome in Patients With Periprosthetic Infection

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2026 to 2026Enrolled200ConditionsPeriprosthetic Joint Infection (PJI)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessandro El MotassimeDepartment of Ageing, Neurosciences, Head-Neck and Orthopaedics Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0001-8331-0826
Elisa PesareOrthopedic Unit, Department of Traslational Biomedicine and Neuroscience DiBraiN, Policlinico di Bari, 70124 Bari, Italy.
Andrea RussoFondazione Policlinico Gemelli, 00168 Rome, Italy.
Sara SaliniFondazione Policlinico Gemelli, 00168 Rome, Italy.
Giordana GavaDepartment of Ageing, Neurosciences, Head-Neck and Orthopaedics Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0008-1459-7625
Carla RecuperoDepartment of Ageing, Neurosciences, Head-Neck and Orthopaedics Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Tommaso GianiDepartment of Ageing, Neurosciences, Head-Neck and Orthopaedics Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Marcello CovinoDepartment of Emergency, Anesthesiological and Reanimation Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-6709-2531
Giulio MaccauroDepartment of Ageing, Neurosciences, Head-Neck and Orthopaedics Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Raffaele VitielloDepartment of Ageing, Neurosciences, Head-Neck and Orthopaedics Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0003-2321-9665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrailty associated with aging increases the risk of falls, disability, and death. The aim of this study is to explore gender-related disparities in the survival outcomes of pathological femoral fractures in older frail patients, while analyzing potential specific prognostic factors.

methodsThis study is a retrospective observational analysis conducted at a single medical center. It enrolled all patients aged 65 and above who were admitted to our emergency department between 2016 and 2020 with a diagnosis of pathological femur fracture requiring surgical intervention. The primary study endpoint was evaluating gender-related differences in survival outcomes. The secondary endpoint involves investigating gender-specific prognostic factors through the analysis of clinical and laboratory parameters.

resultsThe average Charlson Comorbidity Index (CCI) was slightly lower in men, but the difference was not statistically significant (

conclusionFrailty assessment is therefore essential in patients with pathological fracture of the proximal femur and is an important predictor of both gender differences and hospital complications. Enhancing gender analysis in this field is crucial to gather more robust evidence and deeper comprehension of potential sex- and gender-based disparities.

Indexed as

femur fracturesfrailtygenderpathological fractures

Identifiers

PMID39338245
PMCPMC11432814

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.