Evidence map›Paper›PMID 39338151›Full record

ArticleJournal of personalized medicine2024

Psychodynamic Insights into Treatment-Resistant Pharmacotherapy: A Case Study Exploring Patient-Physician Dynamics and Adherence to Evidence-Based Practices.

Alexander Baur, Leslie Kryzanowski

Abstract readCase Reports
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander BaurOrthopaedics Department, Liberty University College of Osteopathic Medicine, Lynchburg, VA 24502, USA.ORCID 0009-0002-9820-6025
Leslie KryzanowskiVirginia Beach Psychiatric Center, Virginia Beach, VA 23454, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPharmacological resistance in severe recurrent mood and anxiety disorders remains a significant challenge in modern biological psychiatry. This case report investigates the intricate decision-making process employed by physicians when managing patients resistant to conventional pharmacotherapy.

methodsInformed consent was obtained from the patient. Following this, the case report was developed using the CARE checklist (2013) to ensure a comprehensive and systematic documentation of the treatment process and outcomes.

resultsThe patient's treatment history highlights the complex nature of pharmacological resistance and the impact of minor medication adjustments versus established clinical practices. A crucial aspect of this case was the patient-physician relationship, particularly addressing the patient's past grievances towards physicians, which played a significant role in the treatment process. Despite efforts to improve the physician's confidence and approach, challenges such as lack of continuity and a fragile therapeutic relationship contributed to treatment failure.

conclusionsThis case underscores the importance of psychodynamic models in overcoming pharmacologic challenges. A deeper understanding of the patient-physician dynamics and addressing underlying emotional factors can enhance treatment efficacy and patient outcomes, providing valuable lessons for managing complex cases of treatment resistance.

Indexed as

anxietybehavioral pharmacologydepressioninsomniapersonality disorderspsychodynamic pharmacologytreatment resistance

Identifiers

PMID39338151
PMCPMC11432977

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