Evidence map›Paper›PMID 39337963›Full record

ArticleLife (Basel, Switzerland)2024

Anti-Coronavirus Activity of Chitosan-Stabilized Liposomal Nanocarriers Loaded with Natural Extracts from Bulgarian Flora.

Anna Gyurova, Viktoria Milkova, Ivan Iliev, Nevena Lazarova-Zdravkova, Viktor Rashev, Lora Simeonova, Neli Vilhelmova-Ilieva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna GyurovaInstitute of Physical Chemistry 'Acad. R. Kaischew', Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Viktoria MilkovaInstitute of Physical Chemistry 'Acad. R. Kaischew', Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-6737-1936
Ivan IlievInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-2480-5116
Nevena Lazarova-ZdravkovaDepartment of Biotechnology, University of Chemical Technology and Metallurgy, 8 Kliment Ohridski, 1756 Sofia, Bulgaria.ORCID 0000-0003-1757-3991
Viktor RashevDepartment of Virology, Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0009-0002-2613-6259
Lora SimeonovaDepartment of Virology, Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0000-0002-3452-908X
Neli Vilhelmova-IlievaDepartment of Virology, Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0000-0003-4772-4471

Funding

European Union: BG-RRP-2.004-0002 Grant of European Union-Next Generation EU: BG-RRP-2.004-0002, "BiOrgaMCT"
6 · The paper itself

Abstract

Disease's severity, mortality rates, and common failures to achieve clinical improvement during the unprecedented COVID-19 pandemic exposed the emergency need for new antiviral therapeutics with higher efficacy and fewer adverse effects. This study explores the potential to encapsulate multi-component plant extracts in liposomes as optimized delivery systems and to verify if they exert inhibitory effects against human seasonal betacoronavirus OC43 (HCoV-OC43) in vitro. The selection of

Indexed as

antiviral activitychitosancoronavirus HCoV-OC43cytotoxicitydrug releaseencapsulationliposomesnatural extractsnatural inhibitors of viral replicationphototoxicity

Identifiers

PMID39337963
PMCPMC11605225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.