Evidence map›Paper›PMID 39337907›Full record

ArticleLife (Basel, Switzerland)2024

Postoperative Thrombocytopenia after Revision Arthroplasty: Features, Diagnostic and Therapeutic Considerations.

Carmen Saguna, Nicoleta Mariana Berbec, Marian Platon, Alexandra Marcoci, Andreea Jercan, Andrei Colita, Mihai Emanuel Gherghe, Dana-Georgiana Nedelea, Romica Cergan, Cristian Scheau and 1 more

Abstract readCase Reports
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Severe intraoperative bleeding as the initial manifestation of de novo immune thrombocytopenia during lumbar spinal fusion: a case report.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Severe Postoperative Epistaxis Revealing Immune Thrombocytopenia: A Case Report.Journal of rhinology : official journal of the Korean Rhinologic Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carmen SagunaHematology Clinic, Coltea Clinical Hospital, 030171 Bucharest, Romania.ORCID 0009-0003-6213-0142
Nicoleta Mariana BerbecHematology Clinic, Coltea Clinical Hospital, 030171 Bucharest, Romania.
Marian PlatonHematology Clinic, Coltea Clinical Hospital, 030171 Bucharest, Romania.
Alexandra MarcociHematology Clinic, Coltea Clinical Hospital, 030171 Bucharest, Romania.
Andreea JercanDepartment of Hematology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Andrei ColitaHematology Clinic, Coltea Clinical Hospital, 030171 Bucharest, Romania.
Mihai Emanuel GhergheDepartment of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.ORCID 0000-0002-2269-511X
Dana-Georgiana NedeleaDepartment of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.
Romica CerganDepartment of Anatomy, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Cristian ScheauDepartment of Radiology and Medical Imaging, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.ORCID 0000-0001-7676-6393
Serban DragosloveanuDepartment of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.ORCID 0000-0001-7403-1684

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 66 year-old male patient who developed severe postoperative thrombocytopenia after revision total hip arthroplasty. The patient underwent surgery in a dedicated orthopedics hospital and was initially managed in the intensive care unit. Upon the development of thrombocytopenia, he was referred to a dedicated hematology clinic for investigation and advanced management. A thorough diagnostic algorithm was employed in order to rule out the main causes of thrombocytopenia. By exclusion, we diagnosed the patient as suffering from a rare and severe form of postoperative thrombocytopenia through an immune mechanism. Although postoperative thrombocytopenia is relatively frequent but transitory and no treatment is required, this condition was refractory to corticosteroids and substitution therapy; however, it quickly responded to treatment with thrombopoietin receptor agonists. The patient recovered and was successfully discharged with normal platelet values. While rare occurrences, alternative causes of thrombocytopenia such as infection, drug-induced, or immune should be considered in patients developing postoperative thrombocytopenia.

Indexed as

disseminated intravascular coagulationdrug-inducedimmune mechanismimmune thrombocytopeniaorthopedicspathophysiologyplateletspostoperative thrombocytopenia

Identifiers

PMID39337907
PMCPMC11432911

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.