Evidence map›Paper›PMID 39337659›Full record

ReviewInternational journal of molecular sciences2024

Graphene-Oxide Peptide-Containing Materials for Biomedical Applications.

Andreea Gostaviceanu, Simona Gavrilaş, Lucian Copolovici, Dana Maria Copolovici

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreea GostaviceanuInstitute for Interdisciplinary Research, Aurel Vlaicu University of Arad, Elena Drăgoi St., No. 2, 310330 Arad, Romania.
Simona GavrilaşInstitute for Interdisciplinary Research, Aurel Vlaicu University of Arad, Elena Drăgoi St., No. 2, 310330 Arad, Romania.ORCID 0000-0002-9051-4130
Lucian CopoloviciInstitute for Interdisciplinary Research, Aurel Vlaicu University of Arad, Elena Drăgoi St., No. 2, 310330 Arad, Romania.ORCID 0000-0002-4454-200X
Dana Maria CopoloviciInstitute for Interdisciplinary Research, Aurel Vlaicu University of Arad, Elena Drăgoi St., No. 2, 310330 Arad, Romania.ORCID 0000-0002-1491-0473

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P4-PCE-2021-0639, within PNCDI III
6 · The paper itself

Abstract

This review explores the application of graphene-based materials (GBMs) in biomedicine, focusing on graphene oxide (GO) and its interactions with peptides and proteins. GO, a versatile nanomaterial with oxygen-containing functional groups, holds significant potential for biomedical applications but faces challenges related to toxicity and environmental impact. Peptides and proteins can be functionalized on GO surfaces through various methods, including non-covalent interactions such as π-π stacking, electrostatic forces, hydrophobic interactions, hydrogen bonding, and van der Waals forces, as well as covalent bonding through reactions involving amide bond formation, esterification, thiol chemistry, and click chemistry. These approaches enhance GO's functionality in several key areas: biosensing for sensitive biomarker detection, theranostic imaging that integrates diagnostics and therapy for real-time treatment monitoring, and targeted cancer therapy where GO can deliver drugs directly to tumor sites while being tracked by imaging techniques like MRI and photoacoustic imaging. Additionally, GO-based scaffolds are advancing tissue engineering and aiding tissues' bone, muscle, and nerve tissue regeneration, while their antimicrobial properties are improving infection-resistant medical devices. Despite its potential, addressing challenges related to stability and scalability is essential to fully harness the benefits of GBMs in healthcare.

Indexed as

GraphitePeptidesAnimalsBiocompatible MaterialsBiosensing TechniquesHumansNanostructuresTissue EngineeringBiocompatible Materialsgraphene oxideGraphitePeptidesantibacterialapplicationsbiomedicinecancergraphenegraphene oxidepeptidesproteins

Identifiers

PMID39337659
PMCPMC11432502

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.