Evidence map›Paper›PMID 39337624›Full record

ArticleInternational journal of molecular sciences2024

The Role of NK and T Cells in Endometriosis.

José Lourenço Reis, Natacha Nurdine Rosa, Catarina Martins, Miguel Ângelo-Dias, Luís Miguel Borrego, Jorge Lima

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
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  5. Review
  6. Enhanced CD56 Expression and Increased Number of CD56American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Endometriosis: An Immunologist's Perspective.International journal of molecular sciences · 2025
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

José Lourenço ReisDepartment of Obstetrics and Gynecology, Hospital da Luz Lisboa, Luz Saúde, 1500-650 Lisboa, Portugal.ORCID 0000-0003-2537-7026
Natacha Nurdine RosaUCD School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-9583-2568
Catarina MartinsCHRC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0003-0353-0421
Miguel Ângelo-DiasCHRC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0001-9933-4075
Luís Miguel BorregoCHRC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0003-4708-438X
Jorge LimaDepartment of Obstetrics and Gynecology, Hospital da Luz Lisboa, Luz Saúde, 1500-650 Lisboa, Portugal.ORCID 0000-0002-0831-2741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis, a debilitating condition, affects one in ten women of reproductive age. Its pathophysiology remains unclear, though deficiencies in immune surveillance are thought to create an environment conducive to the evasion of ectopic endometrial cells from the immune system. Our research explores the immunological impact of endometriosis both locally and systemically, emphasizing natural killer (NK) and T cell subpopulations. We incorporated 62 female patients who underwent laparoscopic surgery; of those, 47 had endometriosis, and 15 were controls. We collected peritoneal fluid (PF) and peripheral blood (PB) samples which were tagged with monoclonal antibodies and subsequently scrutinized using flow cytometry. Our findings revealed significant differences in immunological profiles based on demographic factors and symptomatology. In the endometriosis cohort, there was an increase in PB CD56

Indexed as

EndometriosisKiller Cells, NaturalAdultAscitic FluidCD56 AntigenCD8-Positive T-LymphocytesFemaleFlow CytometryHumansT-LymphocytesCD56 AntigenendometriosisNK cellsperipheral bloodperitoneal fluidT cells

Identifiers

PMID39337624
PMCPMC11432446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.