Evidence map›Paper›PMID 39337620›Full record

ArticleInternational journal of molecular sciences2024

Differential Effect of Omega-3 Fatty Acids on Platelet Inhibition by Antiplatelet Drugs In Vitro.

Ioannis K Koutsaliaris, Despoina Pantazi, Aikaterini N Tsouka, Ourania Argyropoulou, Constantinos C Tellis, Alexandros D Tselepis

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. LPCAT3-dependent remodeling of the phospholipids and lipid rafts is essential for vascular proinflammatory signaling and the development of atherosclerosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioannis K KoutsaliarisAtherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.ORCID 0000-0003-3615-2076
Despoina PantaziAtherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.ORCID 0000-0001-6636-5959
Aikaterini N TsoukaAtherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.ORCID 0000-0002-3287-1367
Ourania ArgyropoulouAtherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.
Constantinos C TellisAtherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.
Alexandros D TselepisAtherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.ORCID 0000-0002-5854-2385

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The omega-3 polyunsaturated fatty acids (PUFAs) Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) exert multiple cardioprotective effects, influencing inflammation, platelet activation, endothelial function and lipid metabolism, besides their well-established triglyceride lowering properties. It is not uncommon for omega-3 PUFAs to be prescribed for hypertriglyceridemia, alongside antiplatelet therapy in cardiovascular disease (CVD) patients. In this regard, we studied the effect of EPA and DHA, in combination with antiplatelet drugs, in platelet aggregation and P-selectin and α

Indexed as

Blood PlateletsFatty Acids, Omega-3Platelet AggregationPlatelet Aggregation InhibitorsP-SelectinAdenosine DiphosphateArachidonic AcidAspirinDocosahexaenoic AcidsEicosapentaenoic AcidHumansLactonesPlatelet Glycoprotein GPIIb-IIIa ComplexPyridinesTicagrelorAdenosine DiphosphateArachidonic AcidAspirinDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3LactonesPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexP-SelectinPyridinesTicagrelorvorapaxarantiplatelet drugsDHAEPAomega-3 fatty acidsplateletsPUFAs

Identifiers

PMID39337620
PMCPMC11432081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.