Evidence map›Paper›PMID 39337460›Full record

ArticleInternational journal of molecular sciences2024

CD4

Liangyu Zhu, Hanxin Wu, Li Peng, Xun Huang, Rui Yang, Weijie Ma, Lei Zhong, Bingxue Li, Jieqin Song, Suyi Luo and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Caffeine-mediated CD39Frontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Liangyu ZhuYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.ORCID 0000-0001-6804-0349
Hanxin WuYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Li PengYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Xun HuangYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Rui YangYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Weijie MaYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Lei ZhongYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Bingxue LiYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.ORCID 0000-0003-4599-8508
Jieqin SongYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Suyi LuoYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Li GaoYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Xinya WuYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Weijiang MaYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.
Fukai BaoYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.ORCID 0000-0003-2652-6660
Aihua LiuYunnan Province Key Laboratory of Children's Major Diseases Research, Department of Pathogen Biology and Immunology, School of Basic Medicine, Kunming Medical University, Kunming 650500, China.

Funding

the National Natural Science Foundation of China 31560051the National Natural Science Foundation of China 32060180the National Natural Science Foundation of China 81560596the National Natural Science Foundation of China 81860644the National Natural Science Foundation of China 82160304the Natural Foundation of Yunnan Province 2017FE467-001the Natural Foundation of Yunnan Province 2019FE001-002
6 · The paper itself

Abstract

Observational studies indicate that variations in peripheral blood mononuclear cell (PBMC) subsets are associated with an increased risk of pulmonary tuberculosis (PTB) and coronavirus disease 2019 (COVID-19), but causal validation is lacking. Here, we combined single-cell expression quantitative trait locus (sc-eQTL) and two-sample mendelian randomization (MR) analyses to elucidate the causal relationship between PBMC subsets and the occurrence of PTB and COVID-19 and verified by RT-qPCR. We observed an increase in the CD4

Indexed as

Antigens, CDCD4-Positive T-LymphocytesCOVID-19Lymphocyte Activation Gene 3 ProteinMendelian Randomization AnalysisQuantitative Trait LociSARS-CoV-2BiomarkersFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyGTP-Binding ProteinsHumansMaleMemory T CellsPolymorphism, Single NucleotideAntigens, CDBiomarkersGTP-Binding ProteinsLag3 protein, humanLymphocyte Activation Gene 3 ProteinCOVID-19eQTLpulmonary tuberculosisscRNA-seqT cell subsets

Identifiers

PMID39337460
PMCPMC11432203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.