Evidence map›Paper›PMID 39337459›Full record

ArticleInternational journal of molecular sciences2024

Polyethylene Glycol/Pullulan-Based Carrier for Silymarin Delivery and Its Potential in Biomedical Applications.

Julia Iwaniec, Karina Niziołek, Patryk Polanowski, Dagmara Słota, Edyta Kosińska, Julia Sadlik, Krzysztof Miernik, Josef Jampilek, Agnieszka Sobczak-Kupiec

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia IwaniecCracow University of Technology, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.
Karina NiziołekCracow University of Technology, CUT Doctoral School, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.ORCID 0000-0001-7970-3478
Patryk PolanowskiCracow University of Technology, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.
Dagmara SłotaCracow University of Technology, CUT Doctoral School, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.ORCID 0000-0002-8570-3594
Edyta KosińskaCracow University of Technology, CUT Doctoral School, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.
Julia SadlikCracow University of Technology, CUT Doctoral School, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.
Krzysztof MiernikCracow University of Technology, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.ORCID 0000-0003-3799-6887
Josef JampilekDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.ORCID 0000-0003-2003-9052
Agnieszka Sobczak-KupiecCracow University of Technology, Faculty of Materials Engineering and Physics, Department of Materials Science, 37 Jana Pawła II Av., 31-864 Krakow, Poland.ORCID 0000-0003-0005-6146

Funding

The Ministry of Science and Higher Education of the Republic of Poland SKN/SP/568478/2023The Slovak Research and Development Agency APVV-22-0133
6 · The paper itself

Abstract

Restoring the structures and functions of tissues along with organs in human bodies is a topic gathering attention nowadays. These issues are widely discussed in the context of regenerative medicine. Excipients/delivery systems play a key role in this topic, guaranteeing a positive impact on the effectiveness of the drugs or therapeutic substances supplied. Advances in materials engineering, particularly in the development of hydrogel biomaterials, have influenced the idea of creating an innovative material that could serve as a carrier for active substances while ensuring biocompatibility and meeting all the stringent requirements imposed on medical materials. This work presents the preparation of a natural polymeric material based on pullulan modified with silymarin, which belongs to the group of flavonoids and derives from a plant called

Indexed as

Drug CarriersGlucansPolyethylene GlycolsSilymarinDrug Delivery SystemsHumansHydrogen-Ion ConcentrationSpectroscopy, Fourier Transform InfraredDrug CarriersGlucansPolyethylene GlycolspullulanSilymarinflavonoidspolyethylene glycolpolymerspullulansilymarin

Identifiers

PMID39337459
PMCPMC11432400

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.