Evidence map›Paper›PMID 39337375›Full record

ArticleInternational journal of molecular sciences2024

Thermophilic Hemicellulases Secreted by Microbial Consortia Selected from an Anaerobic Digester.

Luca Bombardi, Marco Orlando, Martina Aulitto, Salvatore Fusco

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luca BombardiBiochemistry and Industrial Biotechnology (BIB) Laboratory, Department of Biotechnology, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-1001-8496
Marco OrlandoDepartment of Biotechnology and Biosciences, University of Milano Bicocca, 20126 Milano, Italy.ORCID 0000-0002-5914-3052
Martina AulittoDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0002-9162-0920
Salvatore FuscoBiochemistry and Industrial Biotechnology (BIB) Laboratory, Department of Biotechnology, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-2928-3609

Funding

MUR-Italian Ministry of University and Research B31I18000230006Next Generation EU B33C22000660001
6 · The paper itself

Abstract

The rise of agro-industrial activities over recent decades has exponentially increased lignocellulose biomasses (LCB) production. LCB serves as a cost-effective source for fermentable sugars and other renewable chemicals. This study explores the use of microbial consortia, particularly thermophilic consortia, for LCB deconstruction. Thermophiles produce stable enzymes that retain activity under industrial conditions, presenting a promising approach for LCB conversion. This research focused on two microbial consortia (i.e., microbiomes) that were analyzed for enzyme production using a cheap medium, i.e., a mixture of spent mushroom substrate (SMS) and digestate. The secreted xylanolytic enzymes were characterized in terms of temperature and pH optima, thermal stability, and hydrolysis products from LCB-derived polysaccharides. These enzymes showed optimal activity aligning with common biorefinery conditions and outperformed a formulated enzyme mixture in thermostability tests in the digestate. Phylogenetic and genomic analyses highlighted the genetic diversity and metabolic potential of these microbiomes.

Indexed as

BioreactorsExtremophilesLigninAnaerobiosisBacillus licheniformisBacteria, AnaerobicBiocatalysisEnzyme StabilityGlycoside HydrolasesHydrolysisMicrobial ConsortiaPhylogenySecretomeSustainable DevelopmentTemperatureGlycoside HydrolaseshemicellulaseLigninlignocellulosecarbohydrate-active enzymeslignocellulose biomassmicrobial consortiaphylogenetic analysesxylanases

Identifiers

PMID39337375
PMCPMC11432564

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.