Evidence map›Paper›PMID 39337358›Full record

ArticleInternational journal of molecular sciences2024

Antibacterial and Antitumoral Potentials of Phytosynthesized Silver/Silver Oxide Nanoparticles Using Tomato Flower Waste.

Simona Marcu Spinu, Mihaela Dragoi Cudalbeanu, Ionela Avram, Radu Claudiu Fierascu, Petronela Mihaela Rosu, Ana-Maria Morosanu, Carmen Laura Cimpeanu, Narcisa Babeanu, Alina Ortan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Process Optimization ofAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simona Marcu SpinuFaculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania.
Mihaela Dragoi CudalbeanuFaculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania.ORCID 0000-0003-2158-3877
Ionela AvramDepartment of Genetics, University of Bucharest, 1-3 Aleea Portocalelor, 060101 Bucharest, Romania.ORCID 0000-0002-9171-0846
Radu Claudiu FierascuNational Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM Bucharest, 202 Splaiul Independenței, 060021 Bucharest, Romania.ORCID 0000-0003-4224-9157
Petronela Mihaela RosuFaculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania.
Ana-Maria MorosanuInstitute of Biology Bucharest, Romanian Academy, 060031 Bucharest, Romania.ORCID 0000-0001-9383-7296
Carmen Laura CimpeanuFaculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania.
Narcisa BabeanuFaculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania.
Alina OrtanFaculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., 011464 Bucharest, Romania.ORCID 0000-0003-0925-1677

Funding

Ministry of Research, Innovation and Digitization INCDCP-ICECHIM Core program PN 23.06.01.01 (AQUAMAT)University of Agronomic Sciences and Veterinary Medicine of Bucharest Competition IPC 2023, Research Project 846/30.06.2023
6 · The paper itself

Abstract

This study presents the phytosynthesis of silver-based nanoparticles using tomato flower waste extracts for the first time in the literature. The determination of total polyphenolic and flavonoid contents in the extracts showed high gallic acid equivalents (6436-8802 mg GAE/kg dm) and high quercetin equivalents (378-633 mg QE/kg dm), respectively, dependent on the extraction method. By the Ultra Performance Liquid Chromatography technique, 14 polyphenolic compounds were identified and quantified in the tomato flower waste extracts. The abundant phenolic compounds were caffeic acid (36,902-32,217 mg/kg) and chlorogenic acid (1640-1728 mg/kg), and the abundant flavonoid compounds were catechin (292-251 mg/kg) and luteolin (246-108 mg/kg). Transmission electron microscopy of the nanoparticles revealed a particle size range of 14-40 nm. Fourier Transform infrared spectroscopy and X-ray diffraction studies confirmed the phytosynthesis of the silver/silver oxide nanoparticles. These findings hold significant results for the antibacterial and antitumoral potential applications of the obtained nanoparticles, opening new areas for research and development and inspiring further exploration. The impact of this research on the field of metallic nanoparticle phytosynthesis is substantial, as it introduces a novel approach and could lead to significant advancements in the field.

Indexed as

Anti-Bacterial AgentsFlowersMetal NanoparticlesSilverSolanum lycopersicumAntineoplastic AgentsFlavonoidsHumansOxidesPlant ExtractsSilver CompoundsSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsAntineoplastic AgentsFlavonoidsOxidesPlant ExtractsSilverSilver CompoundsHeLa tumor cellsHT29 tumor cellsmetallic nanoparticlespathogenic bacteriaphytochemical profiletomato waste

Identifiers

PMID39337358
PMCPMC11432378

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.