Evidence map›Paper›PMID 39337302›Full record

ArticleInternational journal of molecular sciences2024

In Silico Predicting the Presence of the S100B Motif in Edible Plants and Detecting Its Immunoreactive Materials: Perspectives for Functional Foods, Dietary Supplements and Phytotherapies.

Vincenzo Romano Spica, Veronica Volpini, Federica Valeriani, Giovanni Carotenuto, Manuel Arcieri, Serena Platania, Tiziana Castrignanò, Maria Elisabetta Clementi, Fabrizio Michetti

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vincenzo Romano SpicaDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-2900-6399
Veronica VolpiniDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
Federica ValerianiDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-9478-6299
Giovanni CarotenutoDepartment of Ecological and Biological Sciences, University of Tuscia, Viale dell'Università s.n.c., 01100 Viterbo, Italy.ORCID 0009-0007-5328-4683
Manuel ArcieriDepartment of Health Technology, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.ORCID 0000-0002-2312-7704
Serena PlataniaDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
Tiziana CastrignanòDepartment of Ecological and Biological Sciences, University of Tuscia, Viale dell'Università s.n.c., 01100 Viterbo, Italy.ORCID 0000-0002-0689-6720
Maria Elisabetta ClementiIstituto di Scienze e Tecnologie Chimiche "Giulio Natta" SCITEC-CNR, L.go F. Vito 1, 00168 Rome, Italy.ORCID 0000-0002-4615-7826
Fabrizio MichettiDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0003-2546-0532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protein S100B is a part of the S100 protein family, which consists of at least 25 calcium-binding proteins. S100B is highly conserved across different species, supporting important biological functions. The protein was shown to play a role in gut microbiota eubiosis and is secreted in human breast milk, suggesting a physiological trophic function in newborn development. This study explores the possible presence of the S100B motif in plant genomes, and of S100B-like immunoreactive material in different plant extracts, opening up potential botanical uses for dietary supplementation. To explore the presence of the S100B motif in plants, a bioinformatic workflow was used. In addition, the immunoreactivity of S100B from vegetable and fruit samples was tested using an ELISA assay. The S100B motif was expected in silico in the genome of different edible plants belonging to the Viridiplantae clade, such as

Indexed as

Dietary SupplementsFunctional FoodPlants, EdibleS100 Calcium Binding Protein beta SubunitAmino Acid MotifsComputational BiologyComputer SimulationFruitHumansPhylogenyPhytotherapyPlant ProteinsPlant ProteinsS100 Calcium Binding Protein beta Subunitdietmicrobiotanutraceuticalsplantprotein domainS100B

Identifiers

PMID39337302
PMCPMC11431829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.