Evidence map›Paper›PMID 39337265›Full record

ArticleInternational journal of molecular sciences2024

Discriminating Benign from Malignant Lung Diseases Using Plasma Glycosaminoglycans and Cell-Free DNA.

Alvida Qvick, Sinisa Bratulic, Jessica Carlsson, Bianca Stenmark, Christina Karlsson, Jens Nielsen, Francesco Gatto, Gisela Helenius

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. External Validation of Plasma Glycosaminoglycans as Biomarkers to Improve Lung Cancer Risk Stratification.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  3. Liquid Biopsy in the Clinical Management of Cancers.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alvida QvickDepartment of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0001-6688-947X
Sinisa BratulicDepartment of Life Sciences, Chalmers University of Technology, 412 96 Gothenburg, Sweden.ORCID 0000-0002-1663-2227
Jessica CarlssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0001-8457-7592
Bianca StenmarkDepartment of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0003-4637-8626
Christina KarlssonSchool of Health Sciences, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0002-4669-1367
Jens NielsenDepartment of Life Sciences, Chalmers University of Technology, 412 96 Gothenburg, Sweden.ORCID 0000-0002-9955-6003
Francesco GattoDepartment of Life Sciences, Chalmers University of Technology, 412 96 Gothenburg, Sweden.ORCID 0000-0002-9031-9562
Gisela HeleniusDepartment of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0003-2317-5738

Funding

Lions fund for cancer research Uppsala-Örebro NANyckelfonden-Örebro University Hospital Research Foundation NAUppsala-Örebro Regional research council NA
6 · The paper itself

Abstract

We aimed to investigate the use of free glycosaminoglycan profiles (GAGomes) and cfDNA in plasma to differentiate between lung cancer and benign lung disease, in a cohort of 113 patients initially suspected of lung cancer. GAGomes were analyzed in all samples using the MIRAM

Indexed as

Cell-Free Nucleic AcidsGlycosaminoglycansLung NeoplasmsAdultAgedAged, 80 and overBiomarkers, TumorDiagnosis, DifferentialFemaleHumansLung DiseasesMaleMiddle AgedBiomarkers, TumorCell-Free Nucleic AcidsGlycosaminoglycanscfDNAGAGomeglycosaminoglycanslung cancermultiomics

Identifiers

PMID39337265
PMCPMC11431521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.