Evidence map›Paper›PMID 39337255›Full record

ArticleInternational journal of molecular sciences2024

Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes.

Rezan Amjadi, Sebastiaan Werten, Santosh Kumar Lomada, Clara Baldin, Klaus Scheffzek, Theresia Dunzendorfer-Matt, Thomas Wieland

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rezan AmjadiInstitute of Molecular Biochemistry, Medical University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.ORCID 0000-0001-6403-6182
Sebastiaan WertenDepartment of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.ORCID 0000-0003-2244-9688
Santosh Kumar LomadaExperimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167 Mannheim, Germany.
Clara BaldinDepartment of Microbiology, University of Innsbruck, Technikerstraße 25, 6020 Innsbruck, Austria.ORCID 0000-0002-3895-9511
Klaus ScheffzekInstitute of Molecular Biochemistry, Medical University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.
Theresia Dunzendorfer-MattInstitute of Molecular Biochemistry, Medical University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.ORCID 0000-0002-1315-6317
Thomas WielandExperimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167 Mannheim, Germany.ORCID 0000-0001-8262-8261

Funding

DZHK (German Centre for Cardiovascular Research) MA-Wi2
6 · The paper itself

Abstract

Nucleoside diphosphate kinases (NDPKs) are encoded by

Indexed as

NM23 Nucleoside Diphosphate KinasesAdenosine DiphosphateBinding SitesCrystallography, X-RayCyclic AMPGuanosine DiphosphateHumansMagnesiumModels, MolecularNucleoside-Diphosphate KinaseNucleotidesProtein BindingProtein ConformationSubstrate SpecificityUridine DiphosphateAdenosine DiphosphateCyclic AMPGuanosine DiphosphateMagnesiumNM23 Nucleoside Diphosphate KinasesNME3 protein, humanNucleoside-Diphosphate KinaseNucleotidesUridine Diphosphateenzymatic mechanismmagnesium bindingnme3nucleoside diphosphate kinase CX-ray structure

Identifiers

PMID39337255
PMCPMC11431768

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.