Evidence map›Paper›PMID 39337128›Full record

ArticleJournal of clinical medicine2024

Flap-Free Tendon Coverage Using Autologous Fat Grafts Enhanced with Platelet-Rich Plasma and Growth Factors at a Secondary Level Hospital: A Case Report.

Guadalupe Santamaría Salvador, Esteban Acosta Muñoz, Juan Samaniego Rojas, Charles Hidalgo Quishpe, Juan S Izquierdo-Condoy, Jorge Vasconez-Gonzalez, Esteban Ortiz-Prado

Abstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guadalupe Santamaría SalvadorPlastic and Reconstructive Department, Hospital Vozandes, Quito 170521, Ecuador.
Esteban Acosta MuñozOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito 170513, Ecuador.ORCID 0000-0003-3130-2979
Juan Samaniego RojasPlastic and Reconstructive Department, Hospital Vozandes, Quito 170521, Ecuador.
Charles Hidalgo QuishpePlastic and Reconstructive Department, Hospital Vozandes, Quito 170521, Ecuador.
Juan S Izquierdo-CondoyOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito 170513, Ecuador.ORCID 0000-0002-1178-0546
Jorge Vasconez-GonzalezOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito 170513, Ecuador.ORCID 0000-0003-4573-6217
Esteban Ortiz-PradoOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito 170513, Ecuador.ORCID 0000-0002-1895-7498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutologous fat grafting, enriched with platelet-rich plasma (PRP), has been established as an effective and affordable treatment for various types of wound healing. However, its efficacy in managing wounds with tendon exposure has not been thoroughly investigated.

methodsWe report the case of a 40-year-old male who sustained a severe friction burn on his hand and forearm from a car accident, resulting in significant tissue loss and exposed extensor tendons.

resultsTraditional wound treatment strategies were not implemented due to specific patient circumstances. After initial surgical management failed to prevent necrosis and maintain coverage of the exposed tendons, the patient underwent a novel treatment involving autologous fat grafting combined with PRP and growth factors. The procedure was repeated twice within a month to promote granular tissue formation over that area and facilitate subsequent coverage with an epidermoreticular graft. By day 21 post-initial graft, the exposed tendons were 98% covered with granular tissue. Complete wound coverage was achieved by day 60, and by day 130 the patient had regained 90% functionality of the affected limbs.

conclusionsThis case illustrates the potential of autologous fat grafting combined with PRP and growth factors as a viable, flap-free alternative for covering tendon exposures. This approach not only enhances wound healing but also supports functional recovery, underscoring the need for further research into its broader applicative potentials.

Indexed as

autologous fat graftplatelet-rich plasmaregenerative medicinetendon exposurewound healing

Identifiers

PMID39337128
PMCPMC11432800

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