Evidence map›Paper›PMID 39336123›Full record

ArticleBiology2024

Evaluation of the Therapeutic Potential of Traditionally-Used Natural Plant Extracts to Inhibit Proliferation of a HeLa Cell Cancer Line and Replication of Human Respiratory Syncytial Virus (hRSV).

Ellie N Brill, Natalie G Link, Morgan R Jackson, Alea F Alvi, Jacob N Moehlenkamp, Morgan B Beard, Adam R Simons, Linden C Carson, Ray Li, Breckin T Judd and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Osage Orange (Pathogens (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Ellie N BrillDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Natalie G LinkDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Morgan R JacksonDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Alea F AlviDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Jacob N MoehlenkampDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Morgan B BeardDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Adam R SimonsDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Linden C CarsonDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Ray LiDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Breckin T JuddDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Max N BrassealeDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Emily P BerkmanDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Riley K ParkDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.ORCID 0009-0009-1089-8049
Sedna Cordova-HernandezDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Rebecca Y HoffDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Caroline E YagerDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Meredith C ModelskiDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Milica NenadovichDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.ORCID 0009-0004-4478-3286
Dhruvi SisodiaDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Clayton J ReamesDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Andreas G GeraniosDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Sean T BerthrongDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.
Anne M WilsonDepartment of Chemistry and Biochemistry, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.ORCID 0000-0003-0463-0280
Ashlee H TietjeDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.ORCID 0009-0005-9205-0463
Christopher C StobartDepartment of Biological Sciences, Butler University, 4600 Sunset Ave., Indianapolis, IN 46208, USA.ORCID 0000-0003-1729-9769

Funding

Holcomb Awards Committee - Butler University 028657
6 · The paper itself

Abstract

Traditional approaches employing natural plant products to treat a wide array of ailments have been documented and described for thousands of years. However, there remains limited scientific study of the therapeutic potential or effectiveness of ethnobotanical applications. Increases in the incidence of cancer and emerging infectious diseases demonstrate a growing need for advances in the development of therapeutic options. In this study, we evaluate the therapeutic potential of aqueous extracts prepared from four plants, purple aster

Indexed as

antiviralapoptosiscancerphytochemistryrespiratory syncytial virustraditional medicine

Identifiers

PMID39336123
PMCPMC11429219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.