Evidence map›Paper›PMID 39336076›Full record

ArticleBiology2024

Polymorphism of Folate Metabolism Genes among Ethnic Kazakh Women with Preeclampsia in Kazakhstan: A Descriptive Study.

Lyazzat Kaldygulova, Sauran Yerdessov, Talshyn Ukybassova, Yevgeniy Kim, Dinmukhamed Ayaganov, Andrey Gaiday

Abstract read
In one paragraph

Article in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lyazzat KaldygulovaDepartment of Obstetrics and Gynecology #2, West-Kazakhstan Marat Ospanov Medical University, Aktobe 030012, Kazakhstan.ORCID 0000-0001-9866-8444
Sauran YerdessovDepartment of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0002-6377-7744
Talshyn UkybassovaClinical Academic Department of Women's Health, CF "University Medical Center", Astana 010000, Kazakhstan.
Yevgeniy KimClinical Academic Department of Women's Health, CF "University Medical Center", Astana 010000, Kazakhstan.
Dinmukhamed AyaganovDepartment of Neurology, Psychiatry, and Narcology, West-Kazakhstan Marat Ospanov Medical University, Aktobe 030012, Kazakhstan.
Andrey GaidayDepartment of Obstetrics and Gynecology #2, West-Kazakhstan Marat Ospanov Medical University, Aktobe 030012, Kazakhstan.ORCID 0000-0001-7629-8737

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreeclampsia is a severe multifactorial complication of pregnancy. Studies found associations between folate metabolism genes' polymorphisms and preeclampsia. However, investigations in this field are limited among Asian populations. Thus, the study's aim was to evaluate the prevalence of methionine synthase (

methodsThis was a retrospective study involving 4246 patients' data for the period of 2018-2022. Identification of

resultsThe most common and prevalent mutation was the

conclusionsThe identified levels of

Indexed as

folate metabolismmethionine synthasemethionine synthase reductasemethylenetetrahydrofolate reductaseMTHFRMTRMTRRpreeclampsiapregnancythrombophilia

Identifiers

PMID39336076
PMCPMC11428523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.