Evidence map›Paper›PMID 39335906›Full record

ArticleFoods (Basel, Switzerland)2024

Characterization of Peptide Profiles and the Hypoallergenic and High Antioxidant Activity of Whey Protein Hydrolysate Prepared Using Different Hydrolysis Modes.

Qiang Cui, Yuting Li, Tingli Li, Jie Yu, Guanghui Shen, Xiaomeng Sun, Man Zhou, Zhiqing Zhang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Ameliorative Effects ofFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiang CuiCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0000-0001-8865-4890
Yuting LiCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.
Tingli LiCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.
Jie YuCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.
Guanghui ShenCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0000-0002-5994-9865
Xiaomeng SunKey Laboratory of Dairy Science, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-1132-8584
Man ZhouCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.
Zhiqing ZhangCollege of Food Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0000-0001-5871-6499

Funding

China Dairy Industry Association Dairy Science and Technology Innovation Fund-Mengniu Special Research Support Program CDIAKCJJ-MN-2023-005Science and Technology Department of Sichuan Province 2024NSFSC1254
6 · The paper itself

Abstract

Food proteins and peptides are generally considered a source of dietary antioxidants. The aim of this study was to investigate the antioxidant activity, allergenicity, and peptide profiles of whey protein hydrolysates (WPHs) using different hydrolysis methods. The results demonstrated that the degrees of hydrolysis of the hydrolysates with one-step (O-AD) and two-step (T-AD) methods reached 16.25% and 17.64%, respectively. The size exclusion chromatography results showed that the O-AD had a higher content of >5 and <0.3 kDa, and the distribution of peptide profiles for the two hydrolysates was significantly different. Furthermore, 5 bioactive peptides and 15 allergenic peptides were identified using peptidomics. The peptide profiles and the composition of the master proteins of the O-AD and T-AD were different. The DPPH and ABTS radical scavenging abilities of WPHs were measured, and hydrolysates were found to exhibit a strong radical scavenging ability after being treated using different hydrolysis methods. An enzyme-linked immunosorbent assay showed that the sensitization of WPHs was significantly reduced. This study may provide useful information regarding the antioxidant properties and allergenicity of WPHs.

Indexed as

bioactive propertieshydrolysispeptide profilespeptidomicswhey protein isolate

Identifiers

PMID39335906
PMCPMC11431592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.