Novel Green Strategy to Recover Bioactive Compounds with Different Polarities from Horned Melon Peel.

Teodora Cvanić, Mirjana Sulejmanović, Milica Perović, Jelena Vulić, Lato Pezo, Gordana Ćetković, Vanja Travičić

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Innovative Use of Kiwano Cloud Point Extract in Bioactive Nanoemulsion Development.Foods (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teodora CvanićFaculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.ORCID 0000-0003-3977-1980

Mirjana SulejmanovićFaculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.

Milica PerovićFaculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.

Jelena VulićFaculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.ORCID 0000-0001-9349-7367

Lato PezoEngineering Department, Institute of General and Physical Chemistry, Studentski trg 12/V, 11000 Belgrade, Serbia.ORCID 0000-0002-0704-3084

Gordana ĆetkovićFaculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.ORCID 0000-0002-3175-6076

Vanja TravičićFaculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.ORCID 0000-0003-0302-0851

Funding

Ministry of Education, Science, and Technological Development of the Republic of Serbia 451-03-66/2024-03/200134Provincial Secretariat for Higher Education and Scientific Research of Autonomous Province Vojvodina (Serbia) 142-451-2732/2023-01/01

6 · The paper itself

Abstract

Around 20-30% of the horned melon's weight is peel. This peel is often discarded or underutilized despite containing valuable bioactive compounds. Conventional methods for extracting polyphenols and carotenoids from horned melon peel are typically inefficient, environmentally harmful, or require significant time and energy. The potential of green cloud point extraction (CPE) or green surfactant-based extraction for recovering bioactives with different polarities from this kind of by-product has not been thoroughly investigated. Therefore, this study focused on optimizing CPE process parameters using a one-variable-at-a-time (OVAT) approach. Optimal CPE demonstrated superior yields compared to conventional, ultrasound, microwave, ultrasound-assisted CPE, and microwave-assisted CPE methods. Further, a Plackett-Burman design identified key factors influencing optimal CPE conditions, while artificial neural network (ANN) analysis assessed each input variable's impact on outcomes. Maximum extraction efficiency for total phenolics (352.49 mg GAE/100 g), total carotenoids (16.59 mg β-carotene/100 g), and antioxidant activity (989.02 μmol TE/100 g) was achieved under conditions of: surfactant type = Tween 80, surfactant concentration = 2%; solid:liquid ratio = 1:100; pH = 6612; equilibration temperature = 35 °C; equilibration time = 60 min; salt type = NaCl; salt concentration = 16.4%; centrifugation speed = 7906×

Indexed as

ANNantioxidant activitycarotenoidscloud point extractiongreen chemistryhorned melon peelOVATPlackett–Burman designpolyphenols

Identifiers

PMID39335809

DOI10.3390/foods13182880

PMCPMC11431022

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.