Evidence map›Paper›PMID 39335784›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Imaging in Renal Cell Carcinoma Detection.

Dixon Woon, Shane Qin, Abdullah Al-Khanaty, Marlon Perera, Nathan Lawrentschuk

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A prospective head-to-head comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Trial
  3. Prospective evaluation ofAnnals of nuclear medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Review
  10. Role ofJapanese journal of radiology · 2025
    Review
  11. Article
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  13. Review
  14. Article
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  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dixon WoonDepartment of Urology, Austin Health, Heidelberg, VIC 3084, Australia.
Shane QinDepartment of Urology, Austin Health, Heidelberg, VIC 3084, Australia.ORCID 0000-0002-5159-0448
Abdullah Al-KhanatyDepartment of Urology, Austin Health, Heidelberg, VIC 3084, Australia.
Marlon PereraDepartment of Urology, Austin Health, Heidelberg, VIC 3084, Australia.
Nathan LawrentschukDepartment of Surgery, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0001-8553-5618

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImaging in renal cell carcinoma (RCC) is a constantly evolving landscape. The incidence of RCC has been rising over the years with the improvement in image quality and sensitivity in imaging modalities resulting in "incidentalomas" being detected. We aim to explore the latest advances in imaging for RCC.

methodsA literature search was conducted using Medline and Google Scholar, up to May 2024. For each subsection of the manuscript, a separate search was performed using a combination of the following key terms "renal cell carcinoma", "renal mass", "ultrasound", "computed tomography", "magnetic resonance imaging", "18F-Fluorodeoxyglucose PET/CT", "prostate-specific membrane antigen PET/CT", "technetium-99m sestamibi SPECT/CT", "carbonic anhydrase IX", "girentuximab", and "radiomics". Studies that were not in English were excluded. The reference lists of selected manuscripts were checked manually for eligible articles.

resultsThe main imaging modalities for RCC currently are ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI). Contrast-enhanced US (CEUS) has emerged as an alternative to CT or MRI for the characterisation of renal masses. Furthermore, there has been significant research in molecular imaging in recent years, including FDG PET, PSMA PET/CT,

conclusionsThere will be significant change in the field of imaging in RCC as molecular imaging becomes increasingly popular, which reflects a shift in management to a more conservative approach, especially for small renal masses (SRMs). There is the hope that the improvement in imaging will result in less unnecessary invasive surgeries or biopsies being performed for benign or indolent renal lesions.

Indexed as

18F-FDG PET/CT99mTc-Sestamibi SPECT/CTcarbonic anhydrase IXcomputed tomographyimagingmagnetic resonance imagingoncocytomaPSMA PET/CTrenal cell carcinomaultrasound

Identifiers

PMID39335784
PMCPMC11431198

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.