Evidence map›Paper›PMID 39335690›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Performance Evaluation of Automated Erythrocyte Sedimentation Rate (ESR) Analyzers in a Multicentric Study.

Flaminia Tomassetti, Cinzia Calabrese, Fabio Bertani, Michele Cennamo, Daniela Diamanti, Alfredo Giovannelli, Roberto Guerranti, Roberto Leoncini, Maria Lorubbio, Agostino Ognibene and 5 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Flaminia TomassettiDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0002-6336-814X
Cinzia CalabreseDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Fabio BertaniClinical Pathology and Microbiology Unit, Laboratory Analysis, ASST Lariana, Hospital Sant'Anna, 22100 Como, Italy.ORCID 0000-0002-8724-6403
Michele CennamoClinical Pathology and Microbiology Unit, Laboratory Analysis, ASST Lariana, Hospital Sant'Anna, 22100 Como, Italy.
Daniela DiamantiResearch and Development Department, DIESSE Diagnostica Senese S.p.A., Monteriggioni, 53035 Siena, Italy.ORCID 0000-0002-1078-1889
Alfredo GiovannelliDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Roberto GuerrantiClinical Pathology Unit, Innovation, Experimentation and Clinical and Translational Research Department, University Hospital of S. Maria alle Scotte of Siena, Viale Mario Bracci 16, 53100 Siena, Italy.
Roberto LeonciniClinical Pathology Unit, Innovation, Experimentation and Clinical and Translational Research Department, University Hospital of S. Maria alle Scotte of Siena, Viale Mario Bracci 16, 53100 Siena, Italy.
Maria LorubbioChemical-Clinical Analysis Laboratory, Department of Laboratory Medicine and Transfusion, San Donato Hospital, 52100 Arezzo, Italy.ORCID 0000-0003-2786-0994
Agostino OgnibeneChemical-Clinical Analysis Laboratory, Department of Laboratory Medicine and Transfusion, San Donato Hospital, 52100 Arezzo, Italy.ORCID 0000-0001-5287-4250
Eleonora NicolaiDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0003-1415-9808
Martina PelagalliDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0009-0004-6028-9739
Carolina PieroniResearch and Development Department, DIESSE Diagnostica Senese S.p.A., Monteriggioni, 53035 Siena, Italy.ORCID 0000-0003-2997-2922
Sergio BernardiniDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Massimo PieriDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0002-3463-0268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundErythrocyte Sedimentation Rate (ESR) is an easy test used to diagnose and monitor inflammatory and infectious diseases. The aim of this study was the evaluation of the performance of three ESR automated analyzers, VES-MATIC 5, CUBE 30 TOUCH, and MINI-CUBE, involving four Italian polyclinics in Rome, Siena, Como, and Arezzo, as well as inter-site variability assessment to detect possible device-dependent and operator-dependent influences.

methodsAccuracy analysis was carried out by analyzing the same samples with all three instruments and comparing them with the Westergren method. Precision was assessed with quality control material through intra-run and inter-run precision. Repeatability was estimated by reanalyzing fresh blood samples belonging to three ESR ranges (low, intermediate, and high) six times.

resultsThe results showed a strong correlation (Spearman coefficients R

conclusionsThe study proved that all three automated instruments offer optimal performance for accuracy and precision and are suitable for both large and small facilities without influences of the laboratory environment.

Indexed as

ESRinflammationmethod validationmulticentric study

Identifiers

PMID39335690
PMCPMC11431749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.