Evidence map›Paper›PMID 39335675›Full record

ArticleBiomedicines2024

GastricAITool: A Clinical Decision Support Tool for the Diagnosis and Prognosis of Gastric Cancer.

Rocío Aznar-Gimeno, María Asunción García-González, Rubén Muñoz-Sierra, Patricia Carrera-Lasfuentes, María de la Vega Rodrigálvarez-Chamarro, Carlos González-Muñoz, Enrique Meléndez-Estrada, Ángel Lanas, Rafael Del Hoyo-Alonso

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rocío Aznar-GimenoDepartment of Big Data and Cognitive Systems, Instituto Tecnológico de Aragón, ITA, María de Luna 7-8, 50018 Zaragoza, Spain.ORCID 0000-0003-1415-146X
María Asunción García-GonzálezInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.ORCID 0000-0002-8906-2683
Rubén Muñoz-SierraDepartment of Big Data and Cognitive Systems, Instituto Tecnológico de Aragón, ITA, María de Luna 7-8, 50018 Zaragoza, Spain.
Patricia Carrera-LasfuentesInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
María de la Vega Rodrigálvarez-ChamarroDepartment of Big Data and Cognitive Systems, Instituto Tecnológico de Aragón, ITA, María de Luna 7-8, 50018 Zaragoza, Spain.ORCID 0000-0003-1393-8260
Carlos González-MuñozDepartment of Big Data and Cognitive Systems, Instituto Tecnológico de Aragón, ITA, María de Luna 7-8, 50018 Zaragoza, Spain.
Enrique Meléndez-EstradaDepartment of Big Data and Cognitive Systems, Instituto Tecnológico de Aragón, ITA, María de Luna 7-8, 50018 Zaragoza, Spain.
Ángel LanasInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Rafael Del Hoyo-AlonsoDepartment of Big Data and Cognitive Systems, Instituto Tecnológico de Aragón, ITA, María de Luna 7-8, 50018 Zaragoza, Spain.ORCID 0000-0003-2755-5500

Funding

Instituto de Salud Carlos III Fondo de Investigación Sanitaria/FEDER (PI22/00537)
6 · The paper itself

Abstract

BACKGROUND/

objectiveGastric cancer (GC) is a complex disease representing a significant global health concern. Advanced tools for the early diagnosis and prediction of adverse outcomes are crucial. In this context, artificial intelligence (AI) plays a fundamental role. The aim of this work was to develop a diagnostic and prognostic tool for GC, providing support to clinicians in critical decision-making and enabling personalised strategies.

methodsDifferent machine learning and deep learning techniques were explored to build diagnostic and prognostic models, ensuring model interpretability and transparency through explainable AI methods. These models were developed and cross-validated using data from 590 Spanish Caucasian patients with primary GC and 633 cancer-free individuals. Up to 261 variables were analysed, including demographic, environmental, clinical, tumoral, and genetic data. Variables such as

resultsThe XGBoost algorithm (version 1.7.4) achieved the best performance for diagnosis, with an AUC value of 0.68 using 5-fold cross-validation. As for prognosis, the Random Survival Forest algorithm achieved a C-index of 0.77. Of interest, the incorporation of genetic data into the clinical-demographics models significantly increased discriminatory ability in both diagnostic and prognostic models.

conclusionsThis article presents GastricAITool, a simple and intuitive decision support tool for the diagnosis and prognosis of GC.

Indexed as

artificial intelligenceclinical decision support tooldiagnosisgastric cancerprognosis

Identifiers

PMID39335675
PMCPMC11429470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.