Evidence map›Paper›PMID 39335622›Full record

ArticleBiomedicines2024

Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time.

Raquel López-Vilella, Manuel Pérez Guillén, Borja Guerrero Cervera, Ricardo Gimeno Costa, Iratxe Zarragoikoetxea Jauregui, Francisca Pérez Esteban, Paula Carmona, Tomás Heredia Cambra, Mónica Talavera Peregrina, Azucena Pajares Moncho and 8 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Raquel López-VilellaHeart Failure and Transplant Unit, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.ORCID 0000-0002-9696-2313
Manuel Pérez GuillénCardiovascular Surgery Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Borja Guerrero CerveraCardiology Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.ORCID 0000-0003-3359-8857
Ricardo Gimeno CostaIntensive Care Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Iratxe Zarragoikoetxea JaureguiDepartment of Anesthesiology and Critical Care, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.ORCID 0000-0003-3740-6154
Francisca Pérez EstebanIntensive Care Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Paula CarmonaDepartment of Anesthesiology and Critical Care, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Tomás Heredia CambraCardiovascular Surgery Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Mónica Talavera PeregrinaIntensive Care Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Azucena Pajares MonchoDepartment of Anesthesiology and Critical Care, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Carlos Domínguez-MassaCardiovascular Surgery Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.ORCID 0009-0009-1084-3929
Víctor Donoso TrenadoHeart Failure and Transplant Unit, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Luis Martínez DolzCardiology Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.ORCID 0000-0001-5145-8191
Pilar ArgenteDepartment of Anesthesiology and Critical Care, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Álvaro CastellanosIntensive Care Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Juan Martínez LeónCardiovascular Surgery Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Salvador Torregrosa PuertaCardiovascular Surgery Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Luis Almenar BonetHeart Failure and Transplant Unit, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.ORCID 0000-0002-7710-361X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe direct bridge to urgent heart transplant (HT) with venoarterial extracorporeal membrane oxygenation (VA-ECMO) support has been associated with high morbidity and mortality. The objective of this study is to analyze the morbidity and mortality of patients transplanted with VA-ECMO and compare the presumed differences between various eras over a 17-year timeline.

methodsThis is a prospective, observational study on consecutive patients stabilized with VA-ECMO and transplanted with VA-ECMO from July 2007 to December 2023 at a reference center (98 patients). Objective variables were mortality and morbidity from renal failure, venous thromboembolic disease (VTD), primary graft dysfunction (PGD), the need for tracheostomy, severe myopathy, reoperation, post-transplant ECMO, vascular complications, and sepsis/infection.

resultsThe percentage of patients who reached transplantation without the need for mechanical ventilation has increased over the periods studied. No significant differences were found between the study periods in 30-day mortality (

conclusionsVA-ECMO support as a bridge to HT allows hospital discharge for 3 out of 4 transplanted patients. This survival rate has not changed over the years. The comorbidities associated with this device are frequent and significant.

Indexed as

erasmorbiditymortalityurgent heart transplantationvenoarterial extracorporeal membrane oxygenation

Identifiers

PMID39335622
PMCPMC11428817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.