Evidence map›Paper›PMID 39335607›Full record

ArticleBiomedicines2024

Postoperative Intravenous Iron Infusion in Anemic Colorectal Cancer Patients: An Observational Study.

Leonidas Chardalias, Androniki-Maria Skreka, Nikolaos Memos, Alexandra-Stavroula Nieri, Dimitrios Politis, Marianna Politou, Theodosios Theodosopoulos, Ioannis Papaconstantinou

Abstract read
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In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leonidas Chardalias2nd Surgical Department, Aretaieion University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-3079-6180
Androniki-Maria Skreka2nd Surgical Department, Aretaieion University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Nikolaos Memos2nd Surgical Department, Aretaieion University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Alexandra-Stavroula NieriDepartment of Nursing, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Dimitrios Politis2nd Surgical Department, Aretaieion University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Marianna PolitouHematology Laboratory-Blood Bank, Aretaieion Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Theodosios Theodosopoulos2nd Surgical Department, Aretaieion University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Ioannis Papaconstantinou2nd Surgical Department, Aretaieion University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia is the most common extraintestinal symptom of colorectal cancer, with a prevalence of 30-75%. While the preoperative anemia in this patient population has been well studied and its correction 4-6 weeks prior to surgery is recommended when feasible, there is a paucity of data regarding the management of postoperative anemia, which has a prevalence of up to 87% in these patients. To address this issue, we conducted an observational cohort study of surgically treated postoperative anemic patients with colorectal cancer. The objective of this study was to evaluate the effect of intravenous ferric carboxymaltose on the correction of postoperative anemia by postoperative day 30 (POD30). The primary outcome was the change in hemoglobin on POD30, while the secondary outcomes were the change in iron and other laboratory parameters, postoperative complications and transfusions. The results demonstrated that patients treated with intravenous iron exhibited a significant increase in hemoglobin levels by POD30, along with a concomitant increase in hematocrit, ferritin, and transferrin saturation levels, compared to the control group. The findings imply that patients undergoing colorectal cancer surgery with anemia that was not corrected in the preoperative setting may benefit from early postoperative intravenous iron infusion.

Indexed as

anemiacolorectal cancerferric carboxymaltoseintravenous ironpostoperative anemia

Identifiers

PMID39335607
PMCPMC11428800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.