Evidence map›Paper›PMID 39335575›Full record

ArticleBiomedicines2024

Is Arterial Stiffness Interconnected with Cardiovascular Drug Prescription Patterns, Body Composition Parameters, and the Quality of Blood Pressure Regulation in Hypertensive Patients?

Josipa Radić, Marijana Vučković, Hana Đogaš, Andrea Gelemanović, Andrej Belančić, Mislav Radić

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Josipa RadićDepartment of Internal Medicine, Division of Nephrology and Dialysis, University Hospital of Split, 21000 Split, Croatia.ORCID 0000-0003-2645-7597
Marijana VučkovićDepartment of Internal Medicine, Division of Nephrology and Dialysis, University Hospital of Split, 21000 Split, Croatia.
Hana ĐogašSchool of Medicine, University of Split, 21000 Split, Croatia.ORCID 0000-0002-2188-0006
Andrea GelemanovićMediterranean Institute for Life Sciences (MedILS), 21000 Split, Croatia.ORCID 0000-0001-9195-646X
Andrej BelančićDepartment of Basic and Clinical Pharmacology with Toxicology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20, 51000 Rijeka, Croatia.ORCID 0000-0001-7848-6600
Mislav RadićSchool of Medicine, University of Split, 21000 Split, Croatia.ORCID 0000-0003-0350-6800

Funding

European Regional Development Fund KK.01.1.1.04.0115.
6 · The paper itself

Abstract

backgroundArterial hypertension (AH) is a significant risk factor for cardiovascular disease and is associated with increased arterial stiffness, particularly as measured by pulse wave velocity (PWV). This study aims to explore the relationships between age groups, antihypertensive and new oral antidiabetic drugs, body composition, and arterial stiffness parameters in hypertensive patients.

methodsA single-center cross-sectional study was conducted including 584 participants who underwent 24 h ambulatory blood pressure monitoring (including central blood pressure (BP) and PWV measurement), body composition analysis, and provided medical history and current pharmacotherapy data.

resultsThe study found that PWV was significantly higher in patients with poorly regulated BP in those aged 65 years and older. Significant PWV predictors included systolic BP, heart rate, peripheral mean arterial pressure, peripheral pulse pressure, augmentation index, calcium channel blockers, moxonidine, sodium-glucose co-transporter 2 inhibitors, urapidil, and statin prescription. Also, statistically significant negative correlations were found between PWV and visceral fat level, fat-free mass, and the percentage of muscle mass.

conclusionsThe findings suggest that arterial stiffness is interconnected with peripheral and central blood pressure parameters, body composition parameters, and prescribed hypertensive and new antidiabetic drugs.

Indexed as

antihypertensive medicationarterial hypertensionarterial stiffnessbody compositionpulse wave velocity

Identifiers

PMID39335575
PMCPMC11429216

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.