Evidence map›Paper›PMID 39335529›Full record

ArticleBiomedicines2024

New Neutrophil Parameters in Diseases with Various Inflammatory Processes.

Elżbieta Rutkowska, Iwona Kwiecień, Agata Raniszewska, Rafał Sokołowski, Joanna Bednarek, Karina Jahnz-Różyk, Andrzej Chciałowski, Piotr Rzepecki

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elżbieta RutkowskaLaboratory of Hematology and Flow Cytometry, Department of Internal Medicine and Hematology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Iwona KwiecieńLaboratory of Hematology and Flow Cytometry, Department of Internal Medicine and Hematology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.ORCID 0000-0003-2266-971X
Agata RaniszewskaLaboratory of Hematology and Flow Cytometry, Department of Internal Medicine and Hematology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Rafał SokołowskiDepartment of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, 04-141 Warsaw, Poland.ORCID 0009-0007-1858-7195
Joanna BednarekDepartment of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, 04-141 Warsaw, Poland.
Karina Jahnz-RóżykDepartment of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, 04-141 Warsaw, Poland.ORCID 0000-0002-3505-1858
Andrzej ChciałowskiDepartment of Internal Medicine, Infectious Diseases and Allergology, 04-141 Warsaw, Poland.ORCID 0000-0002-6444-4124
Piotr RzepeckiDepartment of Internal Medicine and Hematology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.

Funding

Military Institute of Medicine-National Research Institute statutory grant number 608.
6 · The paper itself

Abstract

The neutrophils evaluation seems interesting in the initial qualifications of patients with various inflammatory processes. In this study, we presented analysis of neutrophils and new parameters of the complexity (NEUT-GI, NE-WX), maturation (IG), size (NE-FSC, NE-WZ), and neutrophil activities (NEUT-RI, NE-WY) in coronavirus disease 2019 (COVID-19), lung cancer (LC), sarcoidosis (SA), and healthy controls (HCs). Peripheral blood (PB) was collected. The new parameters were examined by the Sysmex XN-1500. The mean absolute value for the IG parameter was the highest in the LC group. The differences in NEUT-RI value between COVID-19 and the HC group were observed. No significant differences were noticed between groups in the NEUT-GI granularity parameter. Neutrophil size assessed by NE-FSC parameter was reduced in all groups compared to HCs. The values of complexity (NE-WX), fluorescence (NE-WY), and size (NE-WZ) were the lowest in the HCs, whereas the highest median proportions of NE-WX, NE-WY, and NE-WZ were in LC patients. Patients from the SA group differed significantly from the HC group only for the NE-WZ parameter. We showed the usefulness of neutrophil parameters and their reactivity, morphology, and exhaustion. A more detailed analysis of blood counts may reveal trends that indicate a disease-specific immune response.

Indexed as

COVID-19hematology analyzerimmature granulocyteslung cancerneutrophil parametersneutrophil scattering itemssarcoidosisSysmex

Identifiers

PMID39335529
PMCPMC11429323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.