Evidence map›Paper›PMID 39335510›Full record

ArticleBiomedicines2024

Impact of Hyponatremia on COVID-19-Related Outcomes: A Retrospective Analysis.

Pedro Maciel de Toledo Piza, Victor Muniz de Freitas, Isabella Aguiar-Brito, Barbara Monique Calsolari-Oliveira, Érika Bevilaqua Rangel

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pedro Maciel de Toledo PizaPaulista School of Medicine, Federal University of São Paulo, São Paulo 04023-062, SP, Brazil.ORCID 0009-0003-1403-376X
Victor Muniz de FreitasPaulista School of Medicine, Federal University of São Paulo, São Paulo 04023-062, SP, Brazil.ORCID 0000-0002-3842-818X
Isabella Aguiar-BritoPaulista School of Medicine, Federal University of São Paulo, São Paulo 04023-062, SP, Brazil.ORCID 0000-0001-5318-7153
Barbara Monique Calsolari-OliveiraPaulista School of Medicine, Federal University of São Paulo, São Paulo 04023-062, SP, Brazil.
Érika Bevilaqua RangelDepartment of Medicine, Nephrology Division, Federal University of São Paulo, São Paulo 04038-031, SP, Brazil.ORCID 0000-0003-0982-2484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSodium disturbances are observed in one-third of patients with COVID-19 and result from multifaceted mechanisms. Notably, hyponatremia is associated with disease progression and mortality.

aimWe aimed to analyze the impact of hyponatremia on COVID-19 outcomes and its correlation with clinical and laboratory parameters during the first wave.

methodsWe evaluated the sodium levels of 558 patients with COVID-19 between 21 March 2020, and 31 July 2020, at a single center. We performed linear regression analyses to explore the correlation of sodium levels with COVID-19-related outcomes, demographic data, signs and symptoms, and laboratory parameters. Next, we conducted Pearson correlation analyses. A

resultsHyponatremia was found in 35.3% of hospitalized patients with COVID-19. This was associated with the need for intensive care transfer (B = -1.210,

conclusionsHyponatremia is a risk factor for adverse outcomes in COVID-19 patients. It is associated with demographic data and clinical and laboratory parameters. Therefore, hyponatremia is an important tool for risk stratification in COVID-19 patients.

Indexed as

COVID-19hyponatremiaoutcomessodium

Identifiers

PMID39335510
PMCPMC11444129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.