Evidence map›Paper›PMID 39335481›Full record

ArticleBiomedicines2024

Investigating Modifiable Risk Factors Across Dementia Subtypes: Insights from the UK Biobank.

Xiangge Ma, Hongjian Gao, Yutong Wu, Xinyu Zhu, Shuicai Wu, Lan Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The importance of modifiable lifestyle factors for episodic memory: a gradient boosted tree analysis.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiangge MaDepartment of Biomedical Engineering, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.ORCID 0009-0003-1403-9491
Hongjian GaoDepartment of Biomedical Engineering, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.ORCID 0000-0002-9902-893X
Yutong WuDepartment of Biomedical Engineering, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.ORCID 0009-0003-1433-8520
Xinyu ZhuDepartment of Biomedical Engineering, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Shuicai WuDepartment of Biomedical Engineering, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Lan LinDepartment of Biomedical Engineering, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.ORCID 0000-0002-3431-2753

Funding

National Natural Science Foundation of China 81971683Natural Science Foundation of Beijing Municipality L182010
6 · The paper itself

Abstract

This study investigates the relationship between modifiable risk factors and dementia subtypes using data from 460,799 participants in the UK Biobank. Utilizing univariate Cox proportional hazards regression models, we examined the associations between 83 modifiable risk factors and the risks of all-cause dementia (ACD), Alzheimer's disease (AD), and vascular dementia (VD). Composite scores for different domains were generated by aggregating risk factors associated with ACD, AD, and VD, respectively, and their joint associations were assessed in multivariable Cox models. Additionally, population attributable fractions (PAF) were utilized to estimate the potential impact of eliminating adverse characteristics of the risk domains. Our findings revealed that an unfavorable medical history significantly increased the risk of ACD, AD, and VD (hazard ratios (HR) = 1.88, 95% confidence interval (95% CI): 1.74-2.03,

Indexed as

Cox analysisdementiapopulation attributable fractionsrisk domainsrisk factors

Identifiers

PMID39335481
PMCPMC11428917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.