Evidence map›Paper›PMID 39335391›Full record

ArticleBrain sciences2024

Transcranial Magnetic Stimulation Facilitates Neural Speech Decoding.

Lindy Comstock, Vinícius Rezende Carvalho, Claudia Lainscsek, Aria Fallah, Terrence J Sejnowski

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lindy ComstockDepartment of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles, CA 90095, USA.ORCID 0000-0001-6650-2239
Vinícius Rezende CarvalhoPostgraduate Program in Electrical Engineering, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0003-1821-1634
Claudia LainscsekComputational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.ORCID 0000-0002-1067-8961
Aria FallahDepartment of Neurosurgery, UCLA, Los Angeles, CA 90095, USA.ORCID 0000-0002-9703-0964
Terrence J SejnowskiComputational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.ORCID 0000-0002-0622-7391

Funding

DDALAB: Identifying Latent States from Neural Recordings with Nonlinear Causal AnalysisRF1MH132664 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEJNOWSKI, TERRENCE J · 2023 to 2023
$1.2M
NIMH NIH HHS RF1 MH132664US-Russia Foundation No. 20-AUG- 647 19-UCLA
6 · The paper itself

Abstract

Transcranial magnetic stimulation (TMS) has been widely used to study the mechanisms that underlie motor output. Yet, the extent to which TMS acts upon the cortical neurons implicated in volitional motor commands and the focal limitations of TMS remain subject to debate. Previous research links TMS to improved subject performance in behavioral tasks, including a bias in phoneme discrimination. Our study replicates this result, which implies a causal relationship between electro-magnetic stimulation and psychomotor activity, and tests whether TMS-facilitated psychomotor activity recorded via electroencephalography (EEG) may thus serve as a superior input for neural decoding. First, we illustrate that site-specific TMS elicits a double dissociation in discrimination ability for two phoneme categories. Next, we perform a classification analysis on the EEG signals recorded during TMS and find a dissociation between the stimulation site and decoding accuracy that parallels the behavioral results. We observe weak to moderate evidence for the alternative hypothesis in a Bayesian analysis of group means, with more robust results upon stimulation to a brain region governing multiple phoneme features. Overall, task accuracy was a significant predictor of decoding accuracy for phoneme categories (F(1,135) = 11.51,

Indexed as

motor theory of speech perceptionneural speech decodingneuromodulationphoneme discriminationtranscranial magnetic stimulation

Identifiers

PMID39335391
PMCPMC11430724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.