Evidence map›Paper›PMID 39335382›Full record

ArticleBrain sciences2024

Comparative Analysis of Brain Coping Mechanisms in Small Left-Hemisphere Lesions: Incidental vs. Symptomatic Gliomas.

Elisa Cargnelutti, Tamara Ius, Marta Maieron, Serena D'Agostini, Miran Skrap, Barbara Tomasino

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisa CargneluttiScientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico E. Medea, Dipartimento/Unità Operativa Pasian di Prato, 33037 Pasian di Prato, Italy.ORCID 0000-0002-8248-6694
Tamara IusNeurosurgery Unit, Head-Neck and Neurosciences Department, Azienda Ospedaliero Universitaria Friuli Centrale, 33100 Udine, Italy.
Marta MaieronDepartment of Physics, Azienda Ospedaliero Universitaria Friuli Centrale, 33100 Udine, Italy.
Serena D'AgostiniNeuroradiology Unit, Department of Radiology, Azienda Ospedaliero Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0009-0003-8777-8340
Miran SkrapNeurosurgery Unit, Head-Neck and Neurosciences Department, Azienda Ospedaliero Universitaria Friuli Centrale, 33100 Udine, Italy.
Barbara TomasinoScientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico E. Medea, Dipartimento/Unità Operativa Pasian di Prato, 33037 Pasian di Prato, Italy.ORCID 0000-0003-3135-2984

Funding

Foundation for Cancer Research in Italy (AIRC) IG 2017 Id.20387Ministero della Salute Ricerca Corrente 2024
6 · The paper itself

Abstract

backgroundIncidentally discovered low-grade gliomas (iLGGs) are very rare and little is still known about their associated functional imaging activation patterns, white-matter status, and plasticity potential. Recent studies shed light on several clinical factors responsible for the good clinical status observed in these patients versus those with their symptomatic counterpart (sLGGs), including small volume. Comparisons were typically carried out by comparing iLGGs with the wider and more heterogeneous sLGG group. In this study, we investigated whether iLGGs affect the brain differently from comparably small sLGGs.

methodStarting from a sample of 13 patients with iLGG, in the current comparative cross-sectional study, we identified a group of patients with sLGGs, primarily matched by lesion volume. We looked for potential differences between the two groups in language-related functional and structural parameters (the fMRI network associated with naming and white-matter fascicles).

resultsThe

conclusionsGiven that small volumes characterized both groups and that demographic variables were comparable, too, we hypothesized that differences between the two groups could be attributed to alternative lesion-related parameters. We discussed these findings from clinical and neurosurgical perspectives.

Indexed as

incidentally discovered low-grade glioma (iLGG)languageneuroplasticityobject-naming networksymptomatic gliomawhite matter

Identifiers

PMID39335382
PMCPMC11429952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.