Evidence map›Paper›PMID 39335345›Full record

ArticleBrain sciences2024

Value of Glycemic Indices for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage: A Retrospective Single-Center Study.

Matthias Manfred Deininger, Miriam Weiss, Stephanie Wied, Alexandra Schlycht, Nico Haehn, Gernot Marx, Anke Hoellig, Gerrit Alexander Schubert, Thomas Breuer

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Association between sustained moderate hyperglycemia within first 48 hours and poor functional outcome after polytrauma: A retrospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthias Manfred DeiningerDepartment of Intensive and Intermediate Care, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-8627-0284
Miriam WeissDepartment of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0001-8820-0805
Stephanie WiedInstitute of Medical Statistics, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0003-0616-6610
Alexandra SchlychtDepartment of Intensive and Intermediate Care, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Nico HaehnDepartment of Intensive and Intermediate Care, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0009-0006-1095-0212
Gernot MarxDepartment of Intensive and Intermediate Care, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
Anke HoelligDepartment of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0001-6798-5703
Gerrit Alexander SchubertDepartment of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0001-9135-6042
Thomas BreuerDepartment of Intensive and Intermediate Care, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0003-3804-8811

Funding

Short Term Program of the Faculty of Medicine RWTH Aachen University not applicable
6 · The paper itself

Abstract

Delayed cerebral ischemia (DCI) is a severe complication following aneurysmal subarachnoid hemorrhage (aSAH), linked to poor functional outcomes and prolonged intensive care unit (ICU) stays. Timely DCI diagnosis is crucial but remains challenging. Dysregulated blood glucose, commonly observed after aSAH, may impair the constant glucose supply that is vital for brain function, potentially contributing to DCI. This study aimed to assess whether glucose indices could help identify at-risk patients and improve DCI detection. This retrospective, single-center observational study examined 151 aSAH patients between 2016 and 2019. Additionally, 70 of these (46.4%) developed DCI and 81 did not (no-DCI). To determine the value of glycemic indices for DCI, they were analyzed separately in patients in the period before (pre-DCI) and after DCI (post-DCI). The time-weighted average glucose (TWAG,

Indexed as

aneurysmal subarachnoid hemorrhageblood glucoseDCIdelayed cerebral ischemiadysglycemiahyperglycemiahypoglycemiaICUTUDRTWAG

Identifiers

PMID39335345
PMCPMC11430037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.