Evidence map›Paper›PMID 39335204›Full record

ArticleCancers2024

Tolerability and Outcomes for Treatment of Older Myxoid Liposarcoma Population.

Reilly A Coombs, Judith Jebastin Thangaiah, Brittany L Siontis, Steven I Robinson, Scott H Okuno, Matthew T Houdek, Meng Xu-Welliver, Thanh P Ho

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Liposarcoma: State of the Art-A Scoping Review.Medical sciences (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reilly A CoombsSchool of Medicine, Medical College of Wisconsin-Central Wisconsin, Wausau, WI 54401, USA.ORCID 0009-0005-3709-2169
Judith Jebastin ThangaiahDepartment of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Brittany L SiontisDepartment of Oncology, Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Steven I RobinsonDepartment of Oncology, Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Scott H OkunoDepartment of Oncology, Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-1297-6946
Matthew T HoudekDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-0390-1018
Meng Xu-WelliverDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-8747-692X
Thanh P HoDepartment of Oncology, Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-7659-5766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyxoid liposarcoma predominantly affects young and middle-aged individuals, and little is known regarding treatment tolerability and outcomes in older patients. This study aims to better understand this older patient population.

methodsThis single institution retrospective study included patients aged 70 years and older with localized (non-metastatic) myxoid liposarcoma.

resultsSixteen patients were included. The median age was 75 years, and 9 (56%) were female. Fourteen (88%) were extremity tumors and two (12%) were trunk. The median tumor size was 10.4 cm (range, 3.6 to 28 cm). Five (31%) tumors had a round cell component. All patients had surgery. Fourteen (88%) had perioperative radiation, and three (19%) had perioperative chemotherapy. One patient had postoperative infection, and one patient had neutropenic fever from preoperative chemotherapy. The median follow up from surgery was 6.3 years. Eight (50%) patients died from MLPS. The median relapse-free survival and overall survival were 34 months and 75 months, respectively.

conclusionsMost older patients with localized MLPS received perioperative radiation therapy with surgery, and few serious toxicities were reported. Even with treatment, half of the patients relapsed.

Indexed as

myxoid liposarcomaolder patientssoft tissue sarcoma

Identifiers

PMID39335204
PMCPMC11430764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.