Evidence map›Paper›PMID 39335196›Full record

ReviewCancers2024

The Role of Whole-Gland and Focal Cryotherapy in Recurrent Prostate Cancer.

Faozia Pio, Andeulazia Murdock, Renee E Fuller, Michael J Whalen

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Current Status of Cryoablation in Prostate Cancer Management.Clinical Medicine Insights. Oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Faozia PioDepartment of Urology, George Washington University School of Medicine, 2300 I St NW, Washington, DC 20052, USA.ORCID 0009-0008-7567-9974
Andeulazia MurdockDepartment of Urology, George Washington University School of Medicine, 2300 I St NW, Washington, DC 20052, USA.ORCID 0009-0004-1922-073X
Renee E FullerDepartment of Urology, George Washington University School of Medicine, 2300 I St NW, Washington, DC 20052, USA.
Michael J WhalenDepartment of Urology, George Washington University School of Medicine, 2300 I St NW, Washington, DC 20052, USA.ORCID 0000-0002-2423-072X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the most common non-cutaneous malignancy in men, with the majority of newly diagnosed patients eligible for active surveillance. Despite definitive treatment, a considerable percentage of men will experience biochemical recurrence and even regional and distant metastatic recurrence after radiation therapy or radical prostatectomy. Salvage prostatectomy, while oncologically effective, poses significant morbidity with poor functional outcomes. Salvage cryotherapy has emerged as a promising alternative for localized recurrence, demonstrating safety and efficacy. This review examines the oncologic and functional outcomes of whole-gland and focal salvage cryotherapy, including disease-free survival, cancer-specific survival, and overall survival. The crucial role of multiparametric prostate MRI and evolving role of next-generation PSMA-targeted PET imaging are also examined. The comparison of outcomes of cryotherapy to other salvage ablation modalities, such as high-intensity focused ultrasound (HIFU), is also explored.

Indexed as

biochemical recurrencecryoablationprostate cancerradiation therapy failuresalvage cryotherapysalvage HIFUsalvage therapy

Identifiers

PMID39335196
PMCPMC11430134

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.