Evidence map›Paper›PMID 39335036›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Persistence and Culturability of

Yousr Dhaouadi, Mohamad Javad Hashemi, Dacheng Ren

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Type II Toxin-Antitoxin Systems inInfection and drug resistance · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yousr DhaouadiDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA.ORCID 0009-0009-8817-9626
Mohamad Javad HashemiDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA.
Dacheng RenDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA.

Funding

Optogenetic Control of Bacterial Persistence to Study Biomaterial InfectionsR21AI185651 · NIAID · UNIVERSITY OF TENNESSEE KNOXVILLE · PI REN, DACHENG · 2024 to 2025
$441k
NIAID NIH HHS R21 AI185651NIH HHS 1R21AI185651, Support year 2024-2026
6 · The paper itself

Abstract

BACKGROUND/

objectivesBacteria are well known to enter dormancy under stress conditions. However, the mechanisms of different dormancy-related phenotypes are still under debate and many questions remain unanswered. This study aims to better understand the effects of toxin gene expression on the dormancy of

methodsThe effects of toxin gene expression on growth, persistence, and culturability were characterized. Specifically, we detailed dose- and time-dependent dormancy of

resultsHigh-level persister formation and strong tolerance to ofloxacin were observed after high-level

conclusionsOverall, this study provides new insights into dormancy induced by toxin gene expression and a more comprehensive view of persistence and culturability. The findings may help develop better control agents against dormant bacterial cells.

Indexed as

arabinosebacteriadormancyHipAofloxacinpersisterVBNC

Identifiers

PMID39335036
PMCPMC11428644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.